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Clinical study on cardiac injury after intensitymodulated radiation therapy for lung cancer |
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Abstract Objective To discuss the manifestations of acute cardiac injury after intensity modulated radiation therapy(IMRT) for lung cancer. Methods Fiftysix patients with lung cancer were selected who had undergone IMRT from December 2014 to June 2016. Electrocardiogram(ECG) and echocardiography examinations were performed on them before IMRT, within one week and two months after IMRT by simultaneously integrated boost technology. Results The incidence of acute cardiac injury was 53.6%(30 cases) after radiotherapy and the injuries were graded in level Ⅰ. Among those patients with acute cardiac injury, there were 24 cases found ECG abnormalities, mainly sinus tachycardia(19 cases), and there were 4 cases with ST-T changes, one case with low voltage in limb lead, two cases with pericardial effusion, and 4 cases with left ventricular systolic dysfunction. Conclusion The incidence of acute cardiac injury is low in patients with lung cancer and most of cardiac injuries are ECG abnormalities.
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