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Abstract Objective To observe the effect of active pacing leads in right ventricular outflow tract(RVOT) septum pacing. Methods We selected 135 patients as research objects who had been implanted with pacemakers in Xinxiang Central Hospital from May 2008 to May 2013. According to different sites of implanted pacing leads, they were divided into four groups: VVI right ventricular apex pacing group(52 cases, group A), VVI right ventricular septum pacing group(31 cases, group B), DDD right ventricular apex pacing group(33 cases, group C), DDD right ventricular septum pacing group(19 cases, group D). The pacing threshold, conductor impedance, QRS duration and heart function related indices immediately, 1 month, 6 months, 12 months, and 24 months after pacemaker implantation were analyzed among the four groups. Results The implantation succeeded in the four groups without any complication. The pacing threshold of group B and D immediately after the operation was higher than that of group A and C, without statistically significant difference(P>0.05). There showed no significant difference in pacing perception and impedance among the four groups. After a followup of 1 year, heart function indices of group D increased compared with those of the other three groups, and the differences were all statistically significant(P<0.05). Conclusion RVOT septum pacing is more coincident with the characteristics of physiological pacing than right ventricular apex pacing, and its adverse effect on heart function and ventricular remodeling is weaker. Hence, DDD RVOT septum pacing is an ideal mode of cardiac pacing.
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