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Investigation on the bonding point of traditional Chinese and Western Chronomedicine through distribution regularity of frequent ventricular premature beat |
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Abstract Objective To investigate the circadian rhythms of frequent ventricular premature beat within 24 hours and its circadian rhythm of traditional Chinese medicine by observing the temporal distribution of frequent ventricular premature beat in 24 h ambulatory electrocardiography(AECG), and to discuss the bonding point of traditional Chinese and Western Chronomedicine through the 4 time points of Zi(23:00-01:00), Mao(05:00-07:00), Wu(11:00-13:00), and You(17:00-19:00). Methods
Four hundred and sixtysix patients were enrolled in the study who had been diagnosed with frequent ventricular premature beat by AECG in our hospital from January 2012 to June 2014 and the diagnostic criteria was the total number of ventricular premature beats>500 times/d. Their fundamental data and the number of ventricular premature beats per hour were recorded. The distribution data of frequent ventricular premature beat within 24 hours were regarded as circular distribution, from which the average angle was calculated by PEMS 3.1 statistical software, hypothesis testing was performed and the central tendency of the occurrence time of ventricular premature beat was statistically analysed. With the help of SPSS 20.0 statistical package, comparison of ventricular premature beats numbers among different time points was made by variance analysis of repeated measurement. ResultsAmong the enrolled 466 patients, the peak time for the occurrence of ventricular premature beat by AECG was around 17:49, corresponding to You, the period of a day from 17:00 to 19:00, while the least total number of ventricular premature beats fell in Zi(23:00-01:00) and Mao(05:00-07:00). The differences of the total numbers of ventricular premature beats among the 4 time points were statistically significant(P<0.05). According to the distribution trend chart within 24 hours, the peak time for the occurrence of ventricular premature beat was 18:00 and the down time was 04:00.ConclusionThis study verified the circadian rhythm of frequent premature ventricular beats, and the correspondence between its peak time and You in traditional Chinese medicine. The circadian rhythm was also consistent with Qi activity rule of heart and the coordination between heart and kidney. It made a preliminary exploration on the combination of Chinese and Western Chronomedicine.
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