Abstract:Objective To observe the microembolic signal(MES) and D-dimer level of atrial fibrillation patients before and after warfarin anticoagulant therapy. Methods A total of 40 persistent atrial fibrillation patients with CHADS2 score≥1 were selected. Each of research object underwent MES monitoring and D-dimer level detection before and after warfarin anticoagulant therapy. We compared the results before and after the treatment. Results Before anticoagulant therapy, there were 12 cases with positive MES and 28 with negative MES; after the treatment, 5 cases were positive in MES and 35 were negative. The positive rate of MES significantly decreased after anticoagulant therapy(30.0% vs. 12.5%,χ2=3.66,P<0.05).The level of D-dimer was (273±81) μg/L before anticoagulant therapy and (170±67) μg/L after the therapy. The level of plasmatic D-dimer significantly reduced after the treatment(t=10.09,P<0.05). Conclusion Both of MES and D-dimer level can be regarded as risk evaluation indicators of embolism in atrial fibrillation patients.
徐云, 王兵, 蒋丽娇, 陆小平, 赵晓英, 王芳. 心房颤动患者抗凝治疗前后微栓子及血浆D-二聚体水平观察[J]. 实用心电学杂志, 2016, 25(3): 210-212.
XU Yun, WANG Bing, JIANG Li-Jiao, LU Xiao-Ping, ZHAO Xiao-Ying, WANG Fang. Observation on microembolic signal and D-dimer level of atrial fibrillation patients before and after anticoagulant therapy. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2016, 25(3): 210-212.
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