Abstract：Objective To investigate the response of cardiovascular system of the non-dipper patients with essential hypertension（EH） during exercising. Methods Ninty five EH patients were taken ambulatory blood pressure（BP）monitoring and treadmill exercise test. According to different nocturnal BP reduction rate，these patients were divided into two groups: group A: non-dipper（n =52），group B: dipper（n =43）.Heart rate，BP response，time and mets were recorded and analyzed. Chronotropic response index（CRI），maximum double rate-pressure product（RPP）and myocardial oxygen consumption （MVO2） were calculated and compared. Results The group A had heart rate blunted response（150.27 ±13.81 vs 162.34±9.63;71.76±13.14 vs 81.46±14.02），P <0.01，0.001;lower CRI than controls （0.86±0.25 vs 0.98±0.17），P <0.05; and chronotropic incompetence occupied 27 cases （ 51.92%）were significantly increased，P <0.05; the systolic BP（SBP）of peak exercise，RPP and MVO2 were significantly higher than the group B， P<0.05. Conclusion Non-dipper patients with EH tends to have a higher incidence of exaggerated SBP and MVO2，and Chronotropic incompetence is common，so rehabilitation should be individual.
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2011, Vol. 20 
