Abstract:ObjectiveTo explore the clinical siginficance of electrocardiogram with upright from children. Methods Color Doppler ultrsound examination was performed on 90 children, aged 7 days to 6 years old, with upright in their electrocardiogram. And the examinaton results as well as clinical diagonsis were analysed. Results The results of color Doppler ultrasound examination showed there were 34 cases with cardiovascular abnormalities(37.8%), 56 cases normal(62.2%); In cardiovascular normal cases, 84% lung infection. ConclusionLung infection and congenital heart disease might be the major cause of upright in children electrocardiogrm.