Abstract:Arrhythmia is one of the common and frequently occurring cardiovascular diseases, and its pathogenesis is closely related to ion channels. K+ channels play important roles in the electrical excitation of cardiomyocytes. The effect of large-conductance Ca2 + -activated K+ channel (BKCa channel) on arrhythmias has become a new direction of research in recent years, and has attracted extensive attention. This paper reviews the biological characteristics of BKCa channel, its distribution in heart tissues and the possible mechanisms of its effect on arrhythmias.
钱玲玲,刘晓宇,王如兴. 大电导钙激活钾通道对心律失常的影响[J]. 实用心电学杂志, 2022, 31(2): 126-129.
QIAN Lingling, LIU Xiaoyu, WANG Ruxing. Effect of large-conductance Ca2+ -activated K + channel on arrhythmias . JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2022, 31(2): 126-129.