摘要 随着对致心律失常性右室心肌病（arrhythmogenic right ventricular cardiomyopathy，ARVC）研究的进展，目前已不再认为ARVC只是桥粒蛋白基因突变引起的一种累及右室的遗传性心肌病。ARVC可以由非桥粒蛋白的多种基因突变或非遗传因素引起，并且可以首先累及左室。因此，2019年制定ARVC诊断标准的国际专家组提出了该病的新的临床分型，并对2010年的诊断标准作出了新的评价。本文就ARVC的临床分型、致病基因、诊断及治疗研究进展等方面进行综述。
Abstract：With the advances of research on arrhythmogenic right ventricular cardiomyopathy (ARVC), it has no longer only been attributed to a kind of right ventricle involved genetic cardiomyopathy resulted from mutations of desmosome protein at present. ARVC can be caused by multiple nondesmosome gene mutations or nongenetic factors, and the left ventricle can be first involved. Therefore, International Task Force proposed a new clinical classification of the disease in 2019, and made a new evaluation of the 2010 diagnostic criteria. This paper reviews on the research development of clinical classification, pathogenic genes, diagnosis and treatment of ARVC.
杨丰菁,刘文玲. 致心律失常性右室心肌病新观点[J]. 实用心电学杂志, 2021, 30(1): 59-63.
YANG Fengjing, LIU Wenling. New viewpoints on arrhythmogenic right ventricular cardiomyopathy. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2021, 30(1): 59-63.
