Abstract：ObjectiveTo investigate the changes and clinical significance of QT dispersion(QTd) in patients with middle and high risk of acute pulmonary embolism before and after thrombolysis. MethodsA total of 44 cases of patients with middle and high risk of acute pulmonary embolism treated with thrombolysis were observed,36 cases of healthy persons with the same age and sex were selected as normal control group.Synchronous 12lead electrocardiogram（ECG) was recorded within 24 hours after admission and 1 week after thrombolysis in patients with acute pulmonary embolism. QT interval was calculated manually. QTd and heart ratecorrected QT dispersion (QTcd) were also calculated. PaO2, blood pressure, heart rate,respiratory rate and respiratory frequency were examined before and after thrombolysis. ResultsQTd and QTcd at admission \[(60.82±6.71) ms, (77.97±6.39) ms\] were significantly higher than those in normal control group \[(31.67±7.98) ms,(34.11±2.48) ms\](P<0.05). QTd and QTcd \[(52.71±6.68) ms,(59.98±11.19) ms\] after thrombolysis therapy were significantly lower than those at admission, but still higher than that of the healthy control group(P<0.05). In addition, after thrombolysis therapy, the clinical symptoms were significantly improved. ConclusionQTd and QTcd in patients with acute pulmonary embolism are increased significantly. QTd is significantly decreased and the clinical symptoms are improved after thrombolysis therapy.
许智永，许以德，林珊婴. 急性肺栓塞患者溶栓治疗前后QT离散度的变化及其临床意义[J]. 实用心电学杂志, 2020, 29(1): 5-7.
Xu Zhiyong,Xu Yide,Lin Shanying. Changes and clinical significance of QT dispersion in patients with acute pulmonary embolism before and after thrombolysis therapy. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2020, 29(1): 5-7.
