Abstract:Objective To study the ECG changes of dispersion indexes of repolarization of ventricular tachycardia(VT) patients with J wave, such as QTd, Tp-e and Tp-e/QT and explore the reasons. Methods For the patients whose J waves were recorded by ECG, divide them into two groups according to the existence of the attack of VT and compare the dispersion indexes of repolarization in ECG. Twentytwo cases with VT and J wave were enrolled, with 12 males and 10 females, at an average age of (52.3±12.3) years old. In the control group, select 56 cases whose ages and genders were matched, with 31 males and 25 females, at an average age of (551.8±10.1) years old. All of the cases enrolled were undergone synchronized 12 lead ECG, with QTd and Tp-e interval measured and the ratio of Tp-e/QT calculated. ResultsCompared with the control group, the value of Tpe increased in the observation group[(89.6 ± 15.1)ms vs. (65.3 ± 14.2) ms, P < 0.001], and so did the ratio of Tp-e/QT(0.22 ± 0.05 vs. 0.16 ± 0.04, P < 0.001), and the differences were statistically significant. However, between the two groups, the difference of QTd showd no statistical significance[(41.1±3.6) ms vs. (38.7±3.9) ms,P>0.05)].ConclusionFor VT patients with J wave, both of the increase of Tpe and Tp-e/QT reflects the increase of dispersion degree of transmural repolarization which indicates big chance of attack of VT arrhythmia.
[1] Boineau JP. The early repolarization variant——an electrocardiographic enigma with both QRS and JSTT anomalies[J]. J Electrocardiol,2007,40(1):3.e1-e10.[2] 陈义汉,龚兰生. QT 离散度[J].中华心血管病杂志,1995,23(4): 307-309.[3] 王红宇.TpTe间期与临床[J].临床心电学杂志,2013,22(4):29-30.[4] Yan GX,Antzelevitch C. Cellular basis for the normal T wave and the electrocardiographic manifestations of the longQT syndrome[J].Circulation,1998,98(18):1928-1936.[5] Gupta P,Patel C,Patel H, et al. T(pe)/QT ratio as an index of arrhythmogenesis[J]. J Electrocardiol,2008,41 (6) : 567-574.[6] Karim Talib A,Sato N,Sakamoto N,et al.Tanabe Y.Enhanced transmural dispersion of repolarization in patients with J wave syndromes[J]. J Cardiovasc Electrophysiol,2012 ,23(10):1109-1114.