中性粒细胞与淋巴细胞比值对缺血性卒中相关性肺炎的预测价值

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	张婷婷
	于明

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Abstract： Objective： To explore the risk factors of stroke-associated pneumonia (SAP) in patients with acute ischemic stroke (AIS) and its clinical significance. Methods： Patients with AIS admitted to the Department of Neurology, Affiliated Hospital of Jiangsu University from February 2021 to June 2022 were selected. According to whether patients had SAP, they were divided into SAP group and nonSAP group. The clinicopathological parameters of the two groups were compared, and the risk factors related to SAP were analyzed by multivariate logistic regression. Receiver operating characteristic (ROC) curve was used to evaluate the value of neutrophil to lymphocyte ratio (NLR) in predicting SAP. Results： Compared with the non-SAP group, patients in the SAP group were older, stayed in hospital longer (P<0.01), had higher NIHSS score, NLR and fasting blood glucose (all P<0.01), had a higher proportion of atrial fibrillation, disturbance of consciousness and dysphagia on admission (P＜0.01). Multiple logistic regression analysis showed that age, length of stay, NLR, NIHSS score and dysphagia were independent risk factors for SAP (P＜0.05). ROC curve analysis revealed that the area under the curve predicted by NLR for SAP was 0.758 (P＜0.05). The optimal cut-off value was 3.962, the sensitivity was 0.699, and the specificity was 0.770. Conclusion： The occurrence of SAP in acute ischemic stroke patients is associated with multiple risk factors, among which high NLR is an independent risk factor and has a certain predictive value for the occurrence of SAP.

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收稿日期: 2023-09-02

基金资助: 中国卒中学会脑血管病全程管理启航基金资助项目；2021年度镇江市分级诊疗创新项目孵化项目(2021ZDX07)；镇江市第六期“169工程”科研项目

通讯作者: 于明(通讯作者)，教授，博士生导师，E-mail： yuming7251@163.com

作者简介: 张婷婷(1993—)，女，硕士，住院医师，主要从事癫痫和脑血管病的研究

引用本文:

张婷婷，于明. 中性粒细胞与淋巴细胞比值对缺血性卒中相关性肺炎的预测价值[J]. 江苏大学学报:医学版, 2024, 24(01): 52-55. ZHANG Tingting, YU Ming. Predictive value of neutrophil-to-lymphocyte ratio for ischemic strokeassociated pneumonia. Journal of Jiangsu University(Medicine Edition), 2024, 24(01): 52-55.

链接本文:

http://zzs.ujs.edu.cn/xbyxb/CN/ 或 http://zzs.ujs.edu.cn/xbyxb/CN/Y2024/V24/I01/52

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