Abstract:The hollow fiber dialysis system was designed and built. The flow and mass characteristics of the blood toxin transport process were experimentally investigated in three different transfer flow paths of inner ring, middle ring and outer ring, and the export concentration and the clearance of toxin were measured. The reason for the nonuniform characteristics in hollow fiber dialyzer were analyzed and discussed. The results show that seriously nonuniform characteristics exist in hollow fiber dialyzer. The clearance effectiveness in the inner ring is very close to that in the middle ring, while a big difference exists between the inner ring and the outer ring. Increasing the dialysate flow rate from 500 mL·min-1 to 1 000 mL·min-1, the export urea concentration deviation is decreased from 15.00% to 6.20%, and the clearance rate deviation is decreased from 16.70% to 5.20% with the significant difference increased from 0.008 to 0.020 between the inner and outer ring. The improvement of clearance efficiency in the inner and middle ring is particularly significant for high dialysate flow rate.
刘涛, 李昌烽, 屈健. 中空纤维管中血液输运过程不均匀特性的试验[J]. 江苏大学学报(自然科学版), 2015, 36(6): 650-654.
LIU Tao, LI Chang-Feng, QU Jian. Experiment of nonuniform characteristics of blood
transport process in hollow fiber dialyzer[J]. Journal of Jiangsu University(Natural Science Eidtion)
, 2015, 36(6): 650-654.