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| Association between plasma sodium and survival in peritoneal dialysis patients |
| YAO Xia-juan, XIA Wen-kai, ZHANG Ying-zi, ZHANG Yao-quan, LIU Jin-hong, HU Hong |
| (Department of Nephrology, the Affiliated Jiangyin Hospital, Medical College of Southeast University, Jiangyin Jiangsu 214400, China） |
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Abstract ［Abstract］Objective： To evaluate the association between plasma sodium and prognosis in peritoneal dialysis patients. Methods： A total of 119 incident peritoneal dialysis were retrospectively selected, and then were followedup by 36 months or until death. The patients were divided into Group Na<135.5 mmol/L and Group Na≥135.5 mmol/L. The patients′ survival rates were analysied by KaplanMeier analysis. Cox proportional hazards analyses were used for elucidating relationship between plasma sodium and allcause mortality in 119 peritoneal dialysis patients. Results： The overall survival rate in Group Na<135.5 mmol/L was significantly lower than Group Na≥135.5 mmol/L (χ2=37.08，P=0.000). By application of Cox proportional hazard model, hyponatremia was independently associated with allcause mortality(HR:1.122， 95%CI:1.043-1.209). Age, serum creatinine and plasma sodium were significantly correlated with poor renal prognosis. Conclusion： Peritoneal dialysis patients with hyponatremia have poor outcome,and serum sodium level may be helpful to predict the patient survival.
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Received: 20 May 2016
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2016, Vol. 26 
