无隧道和涤纶套的透析导管相关性血流感染临床特点及危险因素分析

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Abstract Objective： To explore the clinical characteristics and risk factors of catheterrelated bloodstream infection (CRBSI) in patients undergoing hemodialysis with non-cuffed catheter (NCC). Methods： A retrospective analysis was performed on 169 patients who underwent hemodialysis treatment with ultrasound-guided percutaneous central venous insertion of non-cuffed catheter at the Blood Purification Center, Affiliated Hospital of Jiangsu University from January 2019 to December 2021. The incidence of CRBSI at different catheterization sites was analyzed, and the infection characteristics and pathogenic bacteria distribution of CRBSI patients were analyzed. The patients were divided into infected group (n=22) and noninfected group (n=147) according to whether CRBSI occurred, and the clinicopathological parameters of the two groups were compared. Further, Logistic regression was used to analyze the influencing factors of CRBSI in NCC patients,and receiver operating characteristic (ROC) curve was used to evaluate the prediction effect. Results： There was no significant difference in incidence of CRBSI between internal jugular vein catheterization and femoral vein catheterization (χ2=0.221, P=0.638). A total of 21 strains of pathogenic bacteria were detected in 22 patients with CRBSI, including 16 strains of Gram-positive coccus, mainly Staphylococcus aureus (10 strains) and 5 strains of Gram-negative bacillus. The levels of serum albumin, high-density lipoprotein and serum iron in infected group were significantly lower than those in non-infected group (all P<0.05). Logistic regression analysis showed that serum albumin and high-density lipoprotein were influencing factors for CRBSI in hemodialysis patients (P=0.006, 0.007). ROC curve showed that the AUC of albumin and high-density lipoprotein was 0.726 and 0.704, respectively. Conclusion： Gram-positive bacteria, especially staphylococcus aureus, were the main pathogens causing CRBSI in non-cuffed catheter hemodialysis patients. The low levels of serum albumin and high-density lipoprotein are risk factors for CRBSI.

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Received: 21 August 2023

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	XU Lihua
	HE Jianqiang

Cite this article:

XU Lihua,HE Jianqiang. Clinical characteristics and risk factors of non-cuffed

catheter-related bloodstream infection in hemodialysis patients

[J]. Journal of Jiangsu University(Medicine Edition), 2024, 34(02): 176-179,184.

URL:

http://zzs.ujs.edu.cn/xbyxb/EN/ OR http://zzs.ujs.edu.cn/xbyxb/EN/Y2024/V34/I02/176

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