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| Correlation between CT value of thoracic vertebrae cancellous bone and coronary artery calcification in type 2 diabetes mellitus patients#br# |
| LIU Wen, LU Zukun, WANG Dongqing, ZHU Haitao, SONG Lian, CAO Xiongfeng |
(Department of Imaging, Affiliated Hospital of Jiangsu University, Zhenjiang Jiangsu 212001, China)
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Abstract Objective： To explore the correlation between CT values of thoracic cancellous bone and coronary artery calcification parameters in patients with type 2 diabetes mellitus (T2DM) during single coronary spiral CT scan. Methods： Seventytwo patients with T2DM who underwent 256row Revolution spiral CT scanning from July 2018 to November 2019 were recruited as the study subjects and divided into negative and positive coronary calcification groups. The differences in clinical data and CT measurements of thoracic cancellous bone between the two groups were analyzed. Spearman rank correlation analysis was conducted to analyze the correlation between CT values of cancellous bone of thoracic vertebral body and the degree of coronary artery calcification (number of involved branches and severity). Results： Onetime coronary spiral CT scan can synchronously obtain coronary calcification data and thoracic cancellous bone CT measurements in patients with T2DM, and complete onestop targeted analysis. There were significant differences in age, gender, history of hypertension, duration of diabetes and CT values of thoracic cancellous bone between negative and positive groups (P<0.05 or P＜0.001). CT values of thoracic cancellous bone in T2DM patients were significantly negatively correlated with the number of branches involved in coronary artery calcification (rs=-0.748, P<0.001) and severity (rs=-0.846, P<0.001). Conclusion： In the assessment of the relationship between the severity of coronary artery calcification and bone density in T2DM patients, coronary spiral CT scan can be used to reflect the bone density of patients by simultaneously detecting the CT value of thoracic cancellous bone, which further helps T2DM patients avoid multiple radiation examinations and save time and money.
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Received: 16 January 2023
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