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| Effects of tirofiban treatment on emergency percutaneous coronary intervention in patient with acute coronary syndrome |
| LIU Yi-na, ZHU Jian-hua, WU Xiang, WEI Mei-fang |
| (Department of Cardiology, the Affiliated Hospital of Nantong University, Nantong Jiangsu 226001, China) |
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Abstract Objective: To observe the effects of tirofiban treatment in emergency percutaneous coronary intervention(PCI) of acute coronary syndrome(ACS) patients. Methods: A total of 210 hospitalized patients with ACS were selected, randomly divided into tirofiban group(108) and control group(102). Clinical data, interventional treatment, major adverse cardiac events during hospitalization, incidence of arrhythmia, bleeding complications and related events of two groups were compared. Results:The differences of clinical information, interventional treatment and bleeding complications with the two groups of patients were not statistically significant(P>0.05).Compared with the control group, the incidence of major adverse cardiac events of tirofiban group was significantly reduced during hospitalization. The incidence of bradycardia of tirofiban group was significantly lower than that of control group. Earlier treatment with betablockade in our study was one of the outcomes facilitated by tirofiban treatment. The patients put on tirofiban also experienced less ventricular arrhythmia mandating electric cardioversion/defibrillation. Conclusion: Tirofiban improved the effects of emergency interventional therapy and reduced arrhythmia during operation period in acute coronary syndrome patients. ［Key words］tirofiban; acute coronary syndrome; percutaneous coronary intervention； arrhythmia
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2013, Vol. 23 
