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Viral etiology of hospitalized children with acute respiratory tract infection |
JU Hui-xiang, ZHOU Zhong-wei, ZHU Rong, TANG Qin-fang |
Department of Clinical Laboratory, Affiliated Yancheng Hospital, School of Medicine, Southeast University, Yancheng Jiangsu 224001, China |
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Abstract Objective: To investigate the viral etiology of acute respiratory tract infection(ARI) of hospitalized children in Yancheng of Jiangsu province so as to provide experimental evidence for children with ARI in the area. Methods: The nasopharyngeal aspirate samples from June 2011 to July 2012 were obtained from 1 582 hospitalized children with ARI. Respiratory syncytial virus (RSV), influenza A (IVA), influenza virus B (IVB), parainfluenza virus 1-3 (PIV1-3) and adenovirus were detected by direct immunofluorescence. Results: Four hundred and twenty six case were shown to be infected by respiratory virus in 1582 pediatrics patients and the positive rate was 26.9%. RSV were most frequent(18.3%), followed by adenovirus(2.9%). The overall detection rate of the virus showed significant differences in different age group and seasonal distribution. The highest detection rate of respiratory virus was among children aged 6 month to 1 year and the incidence was higher in winter and spring than in other seasons. Conclusion: RSV and adenovirus was the predominant pathogens of ARI of hospitalized children in Yancheng and the positive rate was significantly associated with age and seasonal distribution.
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Received: 15 August 2012
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