Abstract：Objective: To investigate the relationship between Helicobacter pylori(Hp) infection and coronary heart disease(CHD) in the people of Shanghai.Methods：The selected patients and controls underwent a standard physical examination and questionnaire. Odds ratios(OR) of Hp infection ratio and the hypersensitive C-reactive protein (hs-CRP) level for coronary heart disease were analyzed by logistic regression. Results :Hp infection ratio and hs-CRP level in CHD cases were significantly higher than that of controls(χ2=6.63,t=22.82, P＜0.05). Age and sex adjusted odds ratios of Helicobacter pylori infection ratio and the hs-CRP level for CHD were 1.146(0.722-1.819)，1.073(0.969-1.187), respectively. Fully adjusted odds ratios of Helicobacter pylori infection ratio and the hs-CRP level for CHD were 1.132(0.682-1.877), 1.026(0.918-1.147),respectively. Conclusions：There were no obvious associations between Hp infection ratio and hs-CRP level with coronary heart disease. Hp infection and hs-CRP level should not be considered as the risk factors of CHD for Shanghai people.
收稿日期: 2012-12-07
基金资助:
上海市卫生局科研计划基金资助项目（SW2008092）
通讯作者:
黄学文，主任医师，博士，E-mail:haowei902902@163.com
作者简介: 赵琪（1971—），女，江苏无锡人，副主任技师，主要从事临床检验诊断学研究
引用本文:
赵琪1，安仙园2，黄学文2，封蔚2，罗瑞华2，黄丽丽2，赵兰静2. 幽门螺杆菌和高敏C反应蛋白与冠心病关系的Logistic回归分析[J]. 江苏大学学报:医学版, 2013, 23(1): 26-29,33.
ZHAO Qi1, AN Xian-yuan2, HUANG Xue-wen2, FENG Wei2, LUO Rui-hua2, HUANG Li-li2 , ZHAO Lan-jing2. Logistic regression of the relationships between Helicobacter pylori and hs-CRP with coronary heart disease. Journal of Jiangsu University(Medicine Edition), 2013, 23(1): 26-29,33.
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