[1]Biesiekierski JR, Manning LP, Murray HB, et al. Review article: exclude or expose? The paradox of conceptually opposite treatments for irritable bowel syndrome[J]. Aliment Pharmacol Ther, 2022, 56(4): 592-605.
[2]Quigley EMM, Fried M, Gwee KA, et al. World gastroenterology organisation global guidelines irritable bowel syndrome: a global perspective update September 2015[J]. J Clin Gastroenterol, 2016, 50(9): 704-713.
[3]Lovell RM, Ford AC. Global prevalence of and risk factors for irritable bowel syndrome: a metaanalysis[J]. Clin Gastroenterol Hepatol, 2012, 10(7): 712-721.e4.
[4]Wang YT, Lim HY, Tai D, et al. The impact of irritable bowel syndrome on healthrelated quality of life: a Singapore perspective[J]. BMC Gastroenterol, 2012, 12: 104.
[5]Canavan C, West J, Card T. Review article: the economic impact of the irritable bowel syndrome[J]. Aliment Pharmacol Ther, 2014, 40(9): 1023-1034.
[6]Mahurkar JS, Chang L. Epigenetic mechanisms in irritable bowel syndrome[J]. Front Psychiatry, 2020, 11: 805.
[7]柴玉娜, 唐洪梅, 黄育生, 等. 腹泻型肠易激综合征大鼠SCF/Ckit信号的变化及其与免疫功能的关系[J]. 中国药理学通报, 2018, 34(1): 68-72.
[8]Saito YA, Mitra N, Mayer EA. Genetic approaches to functional gastrointestinal disorders[J]. Gastroenterology, 2010, 138(4): 1276-1285.
[9]Park SH, Videlock EJ, Shih W, et al. Adverse childhood experiences are associated with irritable bowel syndrome and gastrointestinal symptom severity[J]. Neurogastroenterol Motil, 2016, 28(8): 1252-1260.
[10]Parker CH, Naliboff BD, Shih W, et al. Negative events during adulthood are associated with symptom severity and altered stress response in patients with irritable bowel syndrome[J]. Clin Gastroenterol Hepatol, 2019, 17(11): 2245-2252.
[11]Meaney MJ, Szyf M. Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome[J]. Dialogues Clin Neurosci, 2005, 7(2): 103-123.
[12]Feinberg AP. Epigenetics at the epicenter of modern medicine[J]. JAMA, 2008, 299(11): 1345-1350.
[13]Hussain S, Tulsyan S, Dar SA, et al. Role of epigenetics in carcinogenesis: Recent advancements in anticancer therapy[J]. Semin Cancer Biol, 2022, 83: 441-451.
[14]Van Wijnen AJ, Westendorf JJ. Epigenetics as a new frontier in orthopedic regenerative medicine and oncology[J]. J Orthop Res, 2019, 37(7): 1465-1474.
[15]Li Q, Winston JH, Sarna SK. Developmental origins of colon smooth muscle dysfunction in IBSlike rats[J]. Am J Physiol Gastrointest Liver Physiol, 2013, 305(7): G503-G512.
[16]Lu J, Xu J, Li J, et al. FACER: comprehensive molecular and functional characterization of epigenetic chromatin regulators[J]. Nucleic Acids Res, 2018, 46(19): 10019-10033.
[17]Hake SB, Xiao A, Allis CD. Linking the epigenetic ‘language’ of covalent histone modifications to cancer[J]. Br J Cancer, 2004, 90(4): 761-769.
[18]Hong S, Zheng G, Wiley JW. Epigenetic regulation of genes that modulate chronic stressinduced visceral pain in the peripheral nervous system[J]. Gastroenterology, 2015, 148(1): 148-157.e7.
[19]Cohn O, Feldman M, Weil L, et al. Chromatin associated SETD3 negatively regulates VEGF expression[J]. Sci Rep, 2016, 6: 37115.
[20]Theoharides TC, Kavalioti M. Stress, inflammation and natural treatments[J]. J Biol Regul Homeost Agents, 2018, 32(6): 1345-1347.
[21]Chang J, Ji X, Deng T, et al. Setd2 determines distinct properties of intestinal ILC3 subsets to regulate intestinal immunity[J]. Cell Rep, 2022, 38(11): 110530.
[22]Diao D, Wang H, Li T, et al. Telomeric epigenetic response mediated by Gadd45a regulates stem cell aging and lifespan[J]. EMBO Rep, 2018, 19(10): e45494.
[23]Lv Q, Wang K, Qiao S, et al. Norisoboldine, a natural AhR agonist, promotes Treg differentiation and attenuates colitis via targeting glycolysis and subsequent NAD+/SIRT1/SUV39H1/H3K9me3 signaling pathway[J]. Cell Death Dis, 2018, 9(3): 258.
[24]Silverstein RA, Ekwall K. Sin3: a flexible regulator of global gene expression and genome stability[J]. Curr Genet, 2005, 47(1): 1-17.
[25]Kuo MH, Allis CD. Roles of histone acetyltransferases and deacetylases in gene regulation[J]. Bioessays, 1998, 20(8): 615-626.
[26]Kadamb R, Mittal S, Bansal N, et al. Stressmediated Sin3B activation leads to negative regulation of subset of p53 target genes[J]. Biosci Rep, 2015, 35(4): e00234.
[27]Gurley KE, Ashley AK, Moser RD, et al. Synergy between Prkdc and Trp53 regulates stem cell proliferation and GIARS after irradiation[J]. Cell Death Differ, 2017, 24(11): 1853-1860.
[28]Faherty N, Benson M, Sharma E, et al. Negative autoregulation of BMP dependent transcription by SIN3B splicing reveals a role for RBM39[J]. Sci Rep, 2016, 6: 28210.
[29]Robson NC, Hidalgo L, Mc Alpine T, et al. Optimal effector functions in human natural killer cells rely upon autocrine bone morphogenetic protein signaling[J]. Cancer Res, 2014, 74(18): 5019-5031.
[30]Jia X, Sun C. Structural dynamics of the Nterminal domain and the Switch loop of Prp8 during spliceosome assembly and activation[J]. Nucleic Acids Res, 2018, 46(8): 3833-3840.
[31]Blencowe BJ, Nickerson JA, Issner R, et al. Association of nuclear matrix antigens with exoncontaining splicing complexes[J]. J Cell Biol, 1994, 127(3): 593-607.
[32]Ilik I. A, Malszycki M, Lübke AK, et al. SON and SRRM2 are essential for nuclear speckle formation[J]. Elife, 2020, 9: e60579.
[33]Stamm S. Signals and their transduction pathways regulating alternative splicing: a new dimension of the human genome[J]. Hum Mol Genet, 2002, 11(20): 2409-2416.
[34]Zhu YQ, Lu Y, Tan XD. Monochloramine induces reorganization of nuclear speckles and phosphorylation of SRp30 in human colonic epithelial cells: role of protein kinase C[J]. Am J Physiol Cell Physiol, 2003, 285(5): C1294-C1303.
[35]Liu H, Lorenzini PA, Zhang F, et al. Alternative splicing analysis in human monocytes and macrophages reveals MBNL1 as major regulator[J]. Nucleic Acids Res, 2018, 46(12): 6069-6086.
[36]Whisenant TC, Peralta ER, Aarreberg LD, et al. The activationinduced assembly of an RNA/protein interactome centered on the splicing factor U2AF2 regulates gene expression in human CD4 T cells[J]. PLoS One, 2015, 10(12): e0144409.
[37]Kanai T, Totsuka T, Uraushihara K, et al. Blockade of B7H1 suppresses the development of chronic intestinal inflammation[J]. J Immunol, 2003, 171(8): 4156-4163.
[38]Shaw LA, Deng TZ, Omilusik KD, et al. Id3 expression identifies CD4+ memory Th1 cells[J]. Proc Natl Acad Sci U S A, 2022, 119(29): e2204254119.
[39]Chen J, Zhang Y, Deng Z. Imbalanced shift of cytokine expression between T helper 1 and T helper 2 (Th1/Th2) in intestinal mucosa of patients with postinfectious irritable bowel syndrome[J]. BMC Gastroenterol, 2012, 12: 91.
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