Abstract:Objective: To compare the postoperative rehabilitation effect of the goaldirected fluid therapy (GDFT) and the restrictive fluid therapy (RFT) for obese patients undergoing laparoscopic sleeve gastrectomy. Methods: Sixty obese patients who underwent elective laparoscopic sleeve gastrectomy under general anesthesia from May to October 2021 in the Affiliated Hospital of Xuzhou Medical University were selected and divided into RFT group (group RFT) or GDFT (group GDFT) according to the random number table method, with 30 patients in each group. The fluctuation of heart rate and mean arterial pressure in group RFT did not exceed the preoperative baseline 20%. Group GDFT used the FloTrac/Vigileo monitoring system to monitor stroke volume variation (SVV), maintaining SVV≤13%. The incidence of postoperative complications in the two groups was observed. Between the two groups, the use of intraoperative vasoactive drugs and the incidence of intraoperative hypotension were compared; the first postoperative anal exhaust time was compared. The scores of gastrointestinal quality of life index (GIQLI) before and after surgery at 2, 5, 10, 16 weeks were compared. Results: Compared with group RFT, the incidence of postoperative complications in group GDFT was significantly reduced (P<0.05), the utilization of intraoperative vasoactive drugs and the incidence of intraoperative hypotension were also significantly lower (both P<0.05), the first postoperative anal exhaust time was significantly earlier (P<0.01). The GIQLI score in group GDFT was significantly higher than that in group RFT at 2, 5 and 10 weeks after surgery (all P<0.05). Conclusion: The goaldirected fluid therapy based on the FloTrac/Vigileo can promote postoperative rehabilitation of obesity patients.
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