基于冠状动脉CT血管成像的血流储备分数诊断心肌缺血的研究进展

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摘要有创血流储备分数（fractional flow reserve,FFR）是评估由冠状动脉狭窄引起的心肌缺血的“金标准”,但因其有创、费用昂贵,难以在临床广泛应用。近年来,基于冠状动脉CT血管成像（coronary computed tomography angiography,CCTA）的血流储备分数（CTderived fractional flow reserve,CTFFR）已逐渐发展成为检测冠状动脉狭窄引起的心肌缺血的一种新的无创检查方式。目前已有许多国内外学者进行了多中心的临床研究,采用CTFFR从解剖学及血流动力学方面评估冠状动脉狭窄情况,并根据CTFFR结果判断冠脉狭窄是否存在心肌缺血及缺血严重程度,已取得了一定的进展。现本文就CTFFR的概念、基本原理、优势、临床应用现状、局限性及应用前景予以综述。

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	祁冬
	何兴义
	姚木子
	陈冠亚
	董晨
	田欧

关键词 ：冠状动脉, CT血管成像, 血流储备分数, 心肌缺血, 诊断效能, 血流动力学

收稿日期: 2021-08-20

作者简介: 祁冬（1989—）,男,安徽淮北人,主管技师,主要从事医学影像技术及图像后处理。

引用本文:

祁冬,何兴义,姚木子,陈冠亚,董晨,田欧. 基于冠状动脉CT血管成像的血流储备分数诊断心肌缺血的研究进展[J]. 江苏大学学报:医学版, 2022, 22(1): 88-92.

链接本文:

http://zzs.ujs.edu.cn/xbyxb/CN/ 或 http://zzs.ujs.edu.cn/xbyxb/CN/Y2022/V22/I1/88

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