[1]徐萍,徐岷,秦岩,等.老年男性2型糖尿病患者骨质疏松相关因素分析[J].江苏大学学报(医学版), 2016, 26(2): 164-167.
[2]Bone H. Future directions in osteoporosis therapeutics[J].Endocrinol Metab Clin North Am, 2012, 41(3): 655-661.
[3]Papapetrou PD. Bisphosphonateassociated adverse events[J]. Hormones, 2009, 8(2): 96-110.
[4]Iii C, Silverman S, Andriano K,et al. A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. PROOF Study Group[J]. Am J Med, 2000, 109(4): 267-276.
[5]Ma Y,Sato M,Vahle J,et al. Boneneoplasms in F344 rats given teriparatide [rhPTH(134)] are dependent on duration of treatment and dose[J]. Toxicol Pathol, 2004, 32(4): 426-438.
[6]Miller PD,Hattersley G,Riis BJ,et al. Effect of abaloparatide vs placebo on new vertebral fractures in postmenopausal women with osteoporosis: A randomized clinical trial[J]. JAMA, 2016, 316(7): 722-733.
[7]Jolette J, Attalla B,Varela A,et al. Comparing the incidence of bone tumors in rats chronically exposed to the selective PTH type 1 receptor agonist abaloparatide or PTH(1-34)[J]. Regul Toxicol Pharmacol, 2017, 86: 356-365.
[8]Ming LG, Chen KM, Xian CJ, et al. Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling[J]. J Cell Physiol, 2013, 228(3): 513-521.
[9]Fan J, Bi L, Wu T, et al. A combined chitosan/nanosize hydroxyapatite system for the controlled release of icariin[J]. J Mater Sci Mater Med, 2012, 23(2): 399-407.
[10]Zhang X, Xu M, Song L, et al. Effects of compatibility of deproteinized antler cancellous bone with various bioactive factors on their osteogenic potential[J]. Biomaterials, 2013, 34(36): 9103-9114.
[11]Zhao J,Ohba S, Komiyama Y, et al. Icariin: a potential osteoinductive compound for bone tissue engineering[J]. Tissue Eng Part A, 2009, 16(1): 233-243.
[12]Chung BH, Kim JD, Kim CK,et al. Icariin stimulates angiogenesis by activating the MEK/ERK and PI3K/Akt/eNOSdependent signal pathways in human endothelial cells[J].Biochem Biophys Res Commun, 2008, 376(2): 404-408.
[13]Barati D,Shariati SRP,Moeinzadeh S,et al. Spatiotemporal release of BMP2 and VEGF enhances osteogenic and vasculogenic differentiation of human mesenchymal stem cells and endothelial colonyforming cells coencapsulated in a patterned hydrogel[J].J Control Release, 2016, 223: 126-136.
[14]Xiao C, Zhou H, Liu G, et al. Bone marrow stromal cells with a combined expression of BMP2 and VEGF165 enhanced bone regeneration[J].Biomed Mater, 2011, 6(1): 015013.
[15]任格,聂利,杨霞,等.Smad 信号通路在骨形成蛋白 9 促进牙囊干细胞成骨向分化中的研究[J].第三军医大学学报, 2018, 40( 12): 1066-1072.
[16]吉彩霞,刘晓骅,徐丽,等.Runx1 促进 BMP9 诱导的间充质干细胞 MEFs 的成骨分化[J].中国生物工程杂志, 2017, 37(3): 10-17.
[17]乔虎军,王国祥,郝鑫,等.转化生长因子 β/Smad 信号通路和骨关节炎研究进展[J].中国运动医学杂志, 2019, 38(2): 143-151.
[18]余翔,姜自伟,郑晓辉,等.补肾中药调控 BMPSmad 信号通路促进牵张成骨的研究进展[J].辽宁中医杂志, 2017, 44(9): 1991-1994.
[19]徐练,孔清泉.调控成骨细胞分化及骨形成关键信号通路的研究进展[J]. 中国修复重建外科杂志, 2014, 28 (12): 1484-1489.
[20]Zhang D, Fong C, Jia Z, et al. Icariin stimulates differentiation and suppresses adipocytic transdifferentiation of primary osteoblasts through estrogen receptormediated pathway[J]. Calcif Tissue Int, 2016, 99(2): 1-12.
[21]Huang Z, Wei H, Wang X, et al. Icariin promotes osteogenic differentiation of BMSCs by upregulating BMAL1 expression via BMP signaling[J]. Mol Med Rep, 2020, 21(3): 1590-1596.
[22]Song L,Zhao J,Zhang X,et al. Icariin induces osteoblast proliferation, differentiation and mineralization through estrogen receptormediated ERK and JNK signal activation[J]. Eur J Pharmacol, 2013, 714(1-3): 15-22.
[23]朱晓峰, 张荣华, 孙升云,等. 淫羊藿苷通过雌激素受体和p38MAPK信号诱导MC3T3E1Subclone14细胞的分化[J]. 中国老年学杂志, 2012, 32(5): 957-960.
[24]吕明波,刘兴炎,葛宝丰,等.淫羊藿苷对小鼠骨髓源性破骨细胞诱导生成及骨吸收功能的影响[J].中国骨质疏松杂志, 2007, 13(5): 315-319.
[25]李伟娟,谢保平,石丽颖,等.从ERα/RANK通路探讨淫羊藿苷抑制破骨细胞分化作用[J].中国实验方剂学杂志, 2017, 23(7): 121-126.
[26]Chen KM, Ge BF, Liu XY, et al. Icariin inhibits the osteoclast formation induced by RANKL and macrophagecolony stimulating factor in mouse bone marrow culture[J]. Pharmazie, 2007, 62(5): 388-391.
[27]Jian H,Yuan L, Wang X, et al. Icaritin and its glycosides enhance osteoblastic, but suppress osteoclastic, differentiation and activity in vitro[J]. Life Sciences, 2007, 81(10): 832-840.
[28]何丹丹,夏海建,蒋俊,等.淫羊藿素与RANKL蛋白靶点结合抑制破骨细胞分化抗骨质疏松作用研究[J].中草药, 2017, 48(22): 4707-4712.
[29]冯宜蒀,来积芳,董万涛,等.基于网络药理学的“淫羊藿熟地黄”配伍治疗骨质疏松症作用机制研究[J].中国骨质疏松杂志, 2021, 27(6): 875-881.
[30]曾雪, 唐倩, 王丽娟,等. 淫羊藿治疗骨质疏松症的临床疗效[J]. 临床合理用药杂志, 2017, 10(9): 101-102.
[31]刘海燕.中药淫羊藿治疗骨质疏松症的临床观察[J]. 内蒙古中医药, 2019, 38(1): 22-23.
[32]石永新, 逄增金, 羊明智,等. 3D打印技术制备聚磷酸钙/淫羊藿苷骨支架诱导骨髓间充质干细胞成骨分化治疗骨缺损[J]. 中国组织工程研究, 2019, 23(21): 3309-3315.
[33]彭晨健, 杜斌, 孙光权, 等. 3D打印β磷酸三钙支架复合淫羊藿苷微粒修复兔股骨头坏死[J]. 中国组织工程研究, 2019, 23(14): 2162-2168.
[34]王德欣, 许战武, 裴国献. 不同浓度ICAnHA/PLGA复合支架对兔骨髓间充质干细胞增殖分化的影响[J]. 中国骨与关节损伤杂志, 2020, 35(5): 27-29.
[35]Liu H, Li W, Luo B, et al.Icariin immobilized electrospinning poly(llactide) fibrous membranes via polydopamine adhesive coating with enhanced cytocompatibility and osteogenic activity[J]. Mater Sci Eng C Mater Biol Appl, 2017, 79: 399-409.
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