Abstract：Objective: To explore the clinical values of the peripheral soluble fmslike tyrosine kinase receptor 1(sFlt1) levels in early acute coronary syndrome(ACS) patients. Methods: A total of 150 patients who were admitted to hospital in six hours after chest pain occurred were recruited and divided into control group (n=48) or acute coronary syndrome group(ACS, n=102), plasma sFlt1 were detected and compared between the two groups. Receiver operating characteristic(ROC) curve and area under curve(AUC) were analysed with SPSS 20.0 statistical software. Results: The levels of plasma sFlt1 in ACS group were significantly higher compared with that of the control group\[(361.7±288.0) pg/mL vs (126.2±49.6)pg/mL,P<0.01\]. For the diagnosis of ACS, the AUC of sFlt1 was 0.852. Conclusion: Plasma sFlt1 was significantly elevated in the early ACS patients, and it could be one of the earliest sensitive indicators in the diagnosis and risk estimation of ACS.
龚杰， 张煜， 李坚， 羊镇宇. 急性冠脉综合征患者发病早期外周血sFlt-1水平及临床意义[J]. 江苏大学学报:医学版, 2017, 27(01): 58-60.
GONG Jie, ZHANG Yu, LI Jian, YANG Zhen-yu. Levels and the clinical significance of sFlt-1 levels in the early acute coronary syndrome patients. Journal of Jiangsu University(Medicine Edition), 2017, 27(01): 58-60.
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2017, Vol. 27 
