Evaluation of left ventricular systolic function and synchrony in patients with uremic myocardiopathy using two-dimensional speckle tracking
imaging and real-time three-dimensional echocardiography
ZHENG Feng, WANG Jian-fei, XU Li, ZHANG Guo-hui
(Department of Cardiology， the Affiliated People′s Hospital of Jiangsu University，Zhenjiang Jiangsu 212002，China)
Abstract：Objective： Using two-dimensional speckle tracking imaging（2DSTI） and real-time three-dimensional echocardiography(RT-3DE) to evaluate the left ventricular systolic function and synchrony in patients with uremic myocardiopathy(UM). Methods：Thirty-three cases of UM patients and 35 normal subjects were enrolled in this study. The left ventricular end-diastolic internal diameter(LVEDd ), left ventricular end-systolic internal diameter (LVESd), interventr icular septum diameter(IVSd), left ventricular posterior wall diameter(LVPWd) and M-mode ejection fraction(M-EF) were obtained on M-Teichholz method. The twodimensional dynamic gray-scale images of left ventricular short-axis views of the basal, middle and apical plane were acquired. Peak systolic circumferential strain(C.Strain) and Peak systolic circumferential strain rate(C.Strain .Rate) of 16 segments ( except apex cordis） were analysed by Qlab software. RT-3DE was wsed to obtain the left ventricular full-volume images and used Qlab 9.0 software to analyze datas, such as the end diastolic volume(LVEDV) , end-ystolic volume(LVESV) and ejection fraction(EF3d ) of left ventricule, in addition the time to minimal systolic volume (Tmsv) of 16,12,6-segmental standard deviation(Tmsv 16,12,6-SD)was calculated. The maximal difference of correspongding segments(Tmsv 16,12,6-Dif) were also derived from Qlab software, The above parameters as a percentage of the cardiac cycle with different heart rates between patients were also calculated from the Qlab software, which were Tmsv 16,12,6-SD/R-R(%) and Tmsv 16,12,6-Dif/R-R(%), rspectively. Results：The indices of LVEDd, IVSd, LVPWd and LVESV were significantly higher while EF3d were significantly lower in the UM group than those of control group(P<0.05); both C.Strain and C.Strain. rates of UM group were significantly lower than those of control group(P<0.01).As to Tmsv 16-SD, Tmsv 12-SD,Tmsv 6-SD, Tmsv 16-Dif, Tmsv 12-Dif and Tmsv 6-Dif, all parameters in UM group were higher than those of control group (P<0.01) . Conclusion：2DSTI and RT-3DE can be used to evaluate the left ventricular systolic function and synchrony in patients with uremic myocardiopathy more accurately and noninvasively.
［Key words］twodimensional speckle tracking imaging; realtime threedimensional echocardiography; uremic myocardiopathy; left ventricular systolic function; left ventricular systolic synchrony
收稿日期: 2016-08-25
通讯作者:
汪健飞（通讯作者），副主任医师，硕士，E-mail：941015wjf@163.com
作者简介: 郑枫（1983—），女，主治医师，硕士
引用本文:
郑枫, 汪健飞, 徐莉, 张国辉. 二维斑点追踪技术联合实时三维超声心动图评价尿毒症心肌病左心室收缩功能及其同步性[J]. 江苏大学学报:医学版, 2016, 26(06): 532-.
ZHENG Feng, Wang-Jian-Fei, Xu-Li, Zhang-Guo-Hui. Evaluation of left ventricular systolic function and synchrony in patients with uremic myocardiopathy using two-dimensional speckle tracking
imaging and real-time three-dimensional echocardiography. Journal of Jiangsu University(Medicine Edition), 2016, 26(06): 532-.
2016, Vol. 26 
