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Progress in pathogenesis and treatment of atrial fibrillation |
LI Han, CAI Wei |
(Department of Cardiology, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Jiangsu 215000, China)
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Abstract Atrial fibrillation (AF) has become an important disease that endangers the health of middle-aged and elderly people in China, and it is related to the risk of stroke and death. At present, pathophysiological mechanisms such as atrial structural remodeling, electrical remodeling, inflammation, autonomic nervous system disorders, and non-coding RNA may explain the occurrence and development of AF. The treatment of AF mainly includes anticoagulation, conversion of sinus rhythm, and control of ventricular rate. In addition, antiinflammatory, autonomic nerve intervention and genomics intervention therapy may become new types of therapies for AF. This article reviews the research progress in the pathogenesis and treatment of AF.
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