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| Analysis of efficacy, safety and recurrence factors of cryoballoon ablation for atrial fibrillation |
| ZHAO Xiaoxi, LI Kulin, YOU Huayan, ZHENG Jie, DANG Shipeng, LIU Xiaoyu, WANG Ruxing |
| Department of Cardiology, Wuxi Peoples Hospital Affiliated to Nanjing Medical University, Wuxi Jiangsu 214023, China |
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Abstract Objective To investigate the efficacy, safety and recurrence risk factors of cryoballoon ablation for atrial fibrillation(AF). Methods One hundred and fourteen patients were divided into paroxysmal AF group (n=61) and persistent AF group (n=53). Circumferential pulmonary vein cryoablation (CPVC) was performed in all the patients, and persistent AF patients underwent pulmonary vein antrum cryoablation in addition. The operation time, X-ray exposure time, immediate and long-term success rate of CPVC, and procedurerelated complications were analyzed in the two groups. The recurrence rate and related recurrence factors of AF within one year after operation were compared between the two groups.Results The immediate success rates of pulmonary vein isolation are both 100% in the two groups. There are significant differences of the operation time, X-ray exposure time and intraoperative heparin dosage between the two groups (P<0.05). No serious complication is found in either of the two groups. After 12 months of follow-up, the success rates of AF ablation in the paroxysmal and persistent AF groups are 85.25% and 81.13%, respectively (P=0.62). AF duration and left atrial diameter (LAD) are associated with the recurrence of persistent AF. Conclusion Cryoballoon ablation is both effective and safe for patients with paroxysmal and persistent AF. AF duration and LAD before ablation are independent risk factors for postoperative recurrence in persistent AF patients.
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