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| Correlation between ECG QRS amplitude parameters, and blood pressure and left ventricular hypertrophy in essential hypertensives with left ventricular hypertrophy |
| HUANG Mujian, LIN Yujuan, CHEN Dongming, LIANG Huajing, LIN Yufang, LIU Jing |
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Abstract Objective To explore the correlation between ECG QRS amplitude parameters, and blood pressure and left ventricular hypertrophy (LVH) in patients with essential hypertension with left ventricular hypertrophy (EH-LVH). Methods A total of 126 patients with EH-LVH were enrolled as research objects. They were divided into mild group (n=51), moderate group (n=47) and severe group (n=28) according to the degree of LVH. We compared the blood pressure, LVH indexes [left ventricular posterior wall thickness (LVPWT), interventricular septal thickness (IVST) and left ventricular mass index (LVMI)], and ECG QRS amplitude parameters [SVl+RV5 amplitude, the sum of QRS amplitudes of all leads (12∑QRSWA), RⅠ+SⅢ amplitude\] among the three groups. The correlation between QRS amplitude parameters, and blood pressure and LVH indexes was analyzed while the relationship between QRS amplitude parameters and the degree of LVH was also analyzed. Results Systolic blood pressure (SBP) and diastolic blood pressure (DBP) in the severe group are significantly higher than those in the mild and moderate groups while these parameters in the moderate group are also significantly higher than those in the mild group (P<0.05). The LVPWT, IVST and LVMI values of the severe group are significantly higher than those of the mild and moderate groups while the above indexes of the moderate group are also significantly higher than those of the mild group (P<0.05). The RⅠ+SⅢ amplitude, 12∑QRSWA and SVl+RV5 amplitude in the severe group are all significantly lower than those in the mild and moderate groups while these amplitudes of the moderate group are also significantly lower than those in the mild group (P<0.05). Pearson correlation analysis shows that the RⅠ+SⅢ amplitude, 12∑QRSWA and SVl+RV5 amplitude are all negatively correlated with DBP, SBP, LVPWT, IVST and LVMI (P<0.05). The RⅠ+SⅢ amplitude, 12∑QRSWA and SVl+RV5 amplitude are all correlated with the degree of LVH (P<0.05). Conclusion The QRS complex in ECGs of EH-LVH patients are obviously abnormal, presenting as the decrease of the RⅠ+SⅢ amplitude, 12∑QRSWA and SVl+RV5 amplitude, which are closely related to blood pressure and LVH indexes. The degree of LVH could be evaluated by measuring QRS complex in the ECG of EH-LVH patients.
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