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| Dynamic evolution of ECG from de Winter syndrome to acute anterior ST segment elevation myocardial infarction: A retrospective analysis |
| SHEN Deng, QIU Huimin, YE Lu, LIU Zongjun |
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Abstract Objective To investigate the population characteristics and risk factors of de Winter syndrome evolved to acute anterior ST segment elevation myocardial infarction (STEMI). Methods A total of 156 patients diagnosed with acute anterior STEMI (typical anterior STEMI group) and 13 patients with de Winter syndrome evolved to acute anterior STEMI (de Winter evolution group) were enrolled in our study. Retrospective analysis was performed on their clinical data including age, gender, past medical history, echocardiographic results and clinical adverse events. The baseline characteristics between the two groups were compared. ResultsThe median time of ECG evolving from de Winter to ST segment elevation is 29.6 min. Different from typical anterior STEMI group, all of the patients in the de Winter evolution group are young males [(61±26) years old vs. (36±12) years old, P<0.01]; the incidence of hyperlipidemia of the patients in the de Winter evolution group are lower than that of cases in the typical anterior STEMI group (71.8% vs. 23.1%, P<0.01). Coronary angiographic results show that in the de Winter evolution group, the culprit vessels are all anterior descending coronary artery, and the TIMI blood flow is 0-1 (total or near occlusion). Conclusion The ECG manifestation of de Winter syndrome is highrisky, and progressive de Winter syndrome is a subtype of de Winter syndrome which is more common in young males. Percutaneous coronary intervention should be performed as early as possible for these patients.
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| Fund:上海市普陀区卫健系统临床优势学科建设项目(2019ysxk01) |
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