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Surface electrocardiogram changes of secundum atrial septal defect and its relationship with pulmonary hypertension |
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Abstract Objective To investigate the changes of surface electrocardiogram in patients with secundum atrial septal defect(ASD) and its relationship with pulmonary hypertension. MethodsSeventyfour patients with secundum ASD were recruited in the study. The incidence of abnormal electrocardiogram and related risk factors were analyzed. According to the results of echocardiography, the patients were categorized into two subgroups: the normal pulmonary artery pressure(NPAP) and the pulmonary artery hypertension(PAH) groups. The differences of surface electrocardiogram between the two groups were compared. ResultsThe incidence of crochetage R wave, incomplete right bundle branch block(IRBBB) and ST-T changes in the electrocardiogram of ASD patients were 67.6%(50/74), 58.1%(43/74) and 56.8%(42/74), respectively. Older age was significantly associated with IRBBB(OR=1.044, 95%CI=1.009-1.080, P=0.012), whereas atrial defect area was significantly associated with crochetage R wave and ST-T changes(OR=0.139, 95%CI=0.011-1.774, P=0.041; OR=0.221, 95%CI=0.073-0.666, P=0.027). The mean age of patients in PAH group was older than that of NPAP group(P<0.05), and the incidence of complete right bundle branch block and ST-T changes in PAH group were significantly increased(P<0.05). ConclusionSurface electrocardiogram plays an important role in the diagnosis of secundum ASD with or without pulmonary hypertension.
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