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| Investigation of the relationship between the fragmented QRS and N-terminal pro-B-type natriuretic peptide |
| CAO Mu-Gen, ZHANG Wen-Jie, LIN Ping, ZHENG Wei-Ping |
| （1.Department of Cardiology，Fujian Provincial Government Hospital Attached To Fujian Health College，Fuzhou Fujian 350003; 2. Provincial Clinical Medical College of Fujian Medical University，Emergency Center of Fujian Province，Department of Electrocardiogram，Fujian Provincial Hospital，Fuzhou Fujian 350001，China） |
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Abstract Objective To investigate the relationship between the fragmented QRS complex(fQRS) and N-terminal pro-B type natriuretic peptide (NT-proBNP). Methods One hundred and two patients with fQRS were selected, and ninety eight patients with no fQRS and no ventricular block were selected as the control group, to compare the difference in NT-proBNP level between the two groups. Based on the occurrence of fQRS lead, the observation group was divided into three subgroups: 1) limb lead, 2) chest lead, and 3) chest lead and limb lead. By comparing the differences in NT-proBNP level among the subgroups, Spearman correlation analysis was conducted. Results NT-proBNP levels were significantly higher in the fQRS group, compared to the control group (P<0.01); NTproBNP levels were also significantly higher in subgroups 2) chest lead, and 3) the chest lead and the limb lead, compared to subgroup 1) limb lead (P<0.01); compared with subgroup 2)chest lead, subgroup 3) chest lead and limb lead has higher NT-proBNP levels (P<0.01);The NT-proBNP values of three groups have a positive correlation. The distribution range of fQRS lead was positively correlated with the NT-proBNP value.Conclusion NT-proBNP levels in patients with fQRS are higher than those normal person and the distribution range of fQRS lead and NT-proBNP level are positively correlated. It has certain clinical value for the diagnosis and prognosis of patients with chronic heart failure.
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2015, Vol. 24 
