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Abstract Nonsustained ventricular tachycardia(NSVT) has been recorded in a wide range of conditions, from apparently healthy individuals to patients with heart diseases. In the absence of heart disease, the prognosis of NSVT patients is debatable. It indicates increased cardiovascular mortality within the next decades if NSVT is detected during exercise, especially in exercise recovery. In trained athletes, NSVT is considered benign when suppressed by exercise. In acute coronary syndrome patients with non-ST-segment elevation, NSVT occurring beyond 48 h after admission indicates an increased risk of cardiac sudden death, especially when associated with myocardial ischemia. As far as patients with acute myocardial infarction are concerned, NSVT has an adverse prognosis when detected the first 13 to 24 h later after admission. In patients with myocardial infarction treated with reperfusion and beta-blockers, NSVT is not an independent predictor of long-term mortality when other covariates such as left ventricular ejection fraction are taken into account. In hypertrophic cardiomyopathy and most genetic channelopathies patients, NSVT carries prognostic significance, whereas its independent prognostic ability in ischemic heart failure and dilated cardiomyopathy has not been established. The management of patients with NSVT is aimed at treating the underlying heart diseases.
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