Abstract:In recent years, with the worldwide pandemic of corona virus disease 2019 (COVID-19), the safety of anti-infection drugs arouses more and more attention. Hydroxychloroquine alone or combined with azithromycin could cause prolonged QT interval in the ECGs of patients with COVID-19, which may induce severe arrhythmia. According to the clinical evidences reported at home and abroad, the changes of QT interval in COVID-19 patients should be strictly monitored. This paper reviews on the drugs leading to prolonged QT interval, inflammation, age and other factors in COVID-19 patients, and their impact on the prognosis, in order to provide references for clinicians to optimize the treatment options of COVID-19 patients.
王悦,陈舒宁,王德国. 新型冠状病毒感染患者QT间期延长及其不良预后的研究进展[J]. 实用心电学杂志, 2023, 32(5): 319-343.
WANG Yue, CHEN Shuning, WANG Deguo. Advances in research of QT interval prolongation and poor prognosis among patients with corona virus disease 2019. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2023, 32(5): 319-343.