Abstract：In recent years, HisPurkinje conduction system pacing has become a feasible alternative to traditional right ventricular pacing in patients with heart failure requiring for ventricular pacing. Operator is required to place the electrode accurately in the areas of His bundle or left bundle branch, and whether the pacing electrode can be successfully implanted depends to a large extent on the operators understanding of the anatomical distribution features of HisPurkinje conduction system and variability of cardiac structure. This review is aimed to analyze the anatomical characteristics of atrioventricular node, His bundle and the proximal left bundle branch, and the relationship between different anatomical structures of conduction system and the occurrence of conduction block, which serves as a reference for guiding HisPurkinje conduction system pacing.
