[1]Galluzzi L, Vitale I, Aaronson SA, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018[J]. Cell Death Differ, 2018, 25(3): 486-541.
[2]Dixon SJ, Lemberg KM, Lamprecht MR, et al. Ferroptosis: an irondependent form of nonapoptotic cell death[J]. Cell, 2012, 149(5): 1060-1072.
[3]Stockwell BR, Friedmann Angeli JP, Bayir H, et al. Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease[J]. Cell, 2017, 171(2): 273-285.
[4]胡善林, 莫钦国, 罗建芳,等. 铁死亡在肿瘤中的研究进展[J]. 江苏大学学报(医学版), 2020, 30(2): 116-120.
[5]Del Re DP, Amgalan D, Linkermann A, et al. Fundamental mechanisms of regulated cell death and implications for heart disease[J]. Physiol Rev, 2019, 99(4): 1765-1817.
[6]Hu Z, Zhang H, Yang SK, et al. Emerging role of ferroptosis in acute kidney injury[J]. Oxid Med Cell Longev, 2019, 2019: 8010614.
[7]Li Y, Feng D, Wang Z, et al. Ischemiainduced ACSL4 activation contributes to ferroptosismediated tissue injury in intestinal ischemia/reperfusion[J]. Cell Death Differ, 2019, 26(11): 2284-2299.
[8]Xu M, Tao J, Yang Y, et al. Ferroptosis involves in intestinal epithelial cell death in ulcerative colitis[J]. Cell Death Dis, 2020, 11(2): 86.
[9]Gu R, Xia Y, Li P, et al. Ferroptosis and its role in gastric cancer[J]. Front Cell Dev Biol, 2022, 10: 860344.
[10]Song Y, Yang H, Lin R, et al. The role of ferroptosis in digestive system cancer[J]. Oncol Lett, 2019, 18(3): 2159-2164.
[11]Nie J, Lin B, Zhou M, et al. Role of ferroptosis in hepatocellular carcinoma[J]. J Cancer Res Clin Oncol, 2018, 144(12): 2329-2337.
[12]Dolma S, Lessnick SL, Hahn WC, et al. Identification of genotypeselective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells[J]. Cancer Cell, 2003, 3(3): 285-296.
[13]Yang WS, Stockwell BR. Synthetic lethal screening identifies compounds activating irondependent, nonapoptotic cell death in oncogenicRASharboring cancer cells[J]. Chem Biol, 2008, 15(3): 234-245.
[14]Li J, Cao F, Yin HL, et al. Ferroptosis: past, present and future[J]. Cell Death Dis, 2020, 11(2): 88.
[15]Torti SV, Torti FM. Iron and cancer: more ore to be mined[J]. Nat Rev Cancer, 2013, 13(5): 342-355.
[16]Bogdan AR, Miyazawa M, Hashimoto K, et al. Regulators of iron homeostasis: new players in metabolism, cell death, and disease[J]. Trends Biochem Sci, 2016, 41(3): 274-286.
[17]Mancias JD, Wang X, Gygi SP, et al. Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy[J]. Nature, 2014, 509(7498): 105-109.
[18]Hou W, Xie Y, Song X, et al. Autophagy promotes ferroptosis by degradation of ferritin[J]. Autophagy, 2016, 12(8): 1425-1428.
[19]Sun X, Ou Z, Xie M, et al. HSPB1 as a novel regulator of ferroptotic cancer cell death[J]. Oncogene, 2015, 34(45): 5617-5625.
[20]Yang WS, Kim KJ, Gaschler MM, et al. Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis[J]. Proc Natl Acad Sci U S A, 2016, 113(34): E4966-E4975.
[21]Lin Z, Liu J, Kang R, et al. Lipidmetabolism in ferroptosis[J]. Adv Biol(Weinh), 2021, 5(8): e2100396.
[22]Thomas C, Jalil A, Magnani C, et al. LPCAT3 deficiency in hematopoietic cells alters cholesterol and phospholipid homeostasis and promotes atherosclerosis[J]. Atherosclerosis, 2018, 275: 409-418.
[23]Wang B, Tontonoz P. Phospholipid remodeling in physiology and disease[J]. Annu Rev Physiol, 2019, 81: 165-188.
[24]Xu Y, Li X, Cheng Y, et al. Inhibition of ACSL4 attenuates ferroptotic damage after pulmonary ischemiareperfusion[J]. FASEB J, 2020, 34(12): 16262-16275.
[25]Feng J, Lu PZ, Zhu GZ, et al. ACSL4 is a predictive biomarker of sorafenib sensitivity in hepatocellular carcinoma[J]. Acta Pharmacol Sin, 2021, 42(1): 160-170.
[26]Catalá A, Díaz M. Editorial: Impact of lipid peroxidation on the physiology and pathophysiology of cell membranes[J]. Front Physiol, 2016, 7: 423.
[27]Bridges RJ, Natale NR, Patel SA. System x-c cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS[J]. Br J Pharmacol, 2012, 165(1): 20-34.
[28]Toyokuni S, Ito F, Yamashita K, et al. Iron and thiol redox signaling in cancer: An exquisite balance to escape ferroptosis[J]. Free Radic Biol Med, 2017, 108: 610-626.
[29]Friedmann Angeli JP, Conrad M. Selenium and GPX4, a vital symbiosis[J]. Free Radic Biol Med, 2018, 127: 153-159.
[30]Yang WS, SriRamaratnam R, Welsch ME, et al. Regulation of ferroptotic cancer cell death by GPX4[J]. Cell, 2014, 156(1-2): 317-331.
[31]Bersuker K, Hendricks JM, Li Z, et al. The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis[J]. Nature, 2019, 575(7784): 688-692.
[32]Doll S, Freitas FP, Shah R, et al. FSP1 is a glutathioneindependent ferroptosis suppressor[J]. Nature, 2019, 575(7784): 693-698.
[33]Mazure NM. VDAC in cancer[J]. Biochim Biophys Acta Bioenerg, 2017, 1858(8): 665-673.
[34]Yagoda N, von Rechenberg M, Zaganjor E, et al. RASRAFMEKdependent oxidative cell death involving voltagedependentanion channels[J]. Nature, 2007, 447(7146): 864-868.
[35]McBean GJ. The transsulfuration pathway: a source of cysteine for glutathione in astrocytes[J]. Amino Acids, 2012, 42(1): 199-205.
[36]Sun X, Ou Z, Chen R, et al. Activation of the p62Keap1NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells[J]. Hepatology, 2016, 63(1): 173-184.
[37]Kraft VAN, Bezjian CT, Pfeiffer S, et al. GTP cyclohydrolase 1/tetrahydrobiopterin counteract ferroptosis through lipid remodeling[J]. ACS Cent Sci, 2020, 6(1): 41-53.
[38]Gao M, Monian P, Quadri N, et al. Glutaminolysis and transferrin regulate ferroptosis[J]. Mol Cell, 2015, 59(2): 298-308.
[39]Akbari G. Emerging roles of microRNAs in intestinal ischemia/reperfusioninduced injury: a review[J]. J Physiol Biochem, 2020, 76(4): 525-537.
[40]Cheng J, Wei Z, Liu X, et al. The role of intestinal mucosa injury induced by intraabdominal hypertension in the development of abdominal compartment syndrome and multiple organ dysfunction syndrome[J]. Crit Care, 2013, 17(6): R283.
[41]Wang Z, Sun R, Wang G, et al. SIRT3mediated deacetylation of PRDX3 alleviates mitochondrial oxidative damage and apoptosis induced by intestinal ischemia/reperfusion injury[J]. Redox Biol, 2020, 28: 101343.
[42]Wen S, Ling Y, Yang W, et al. Necroptosis is a key mediator of enterocytes loss in intestinal ischaemia/reperfusion injury[J]. J Cell Mol Med, 2017, 21(3): 432-443.
[43]Li Z, Wang G, Feng D, et al. Targeting the miR6653pATG4Bautophagy axis relieves inflammation and apoptosis in intestinal ischemia/reperfusion[J]. Cell Death Dis, 2018, 9(5): 483.
[44]Hu Y, Mao Z, Xu L, et al. Protective effect of dioscin against intestinal ischemia/reperfusion injury via adjusting miR3515pmediated oxidative stress[J]. Pharmacol Res, 2018, 137: 56-63.
[45]Balogh N, Krausz F, Lévai P, et al. Effect of deferoxamine and Larginine treatment on lipid peroxidation in an intestinal ischaemiareperfusion model in rats[J]. Acta Vet Hung, 2002, 50(3): 343-356.
[46]Deng F, Zhao BC, Yang X, et al. The gut microbiota metabolite capsiate promotes Gpx4 expression by activating TRPV1 to inhibit intestinal ischemia reperfusioninduced ferroptosis[J]. Gut Microbes, 2021, 13(1): 1-21.
[47]Sartor RB, Wu GD. Roles for intestinal bacteria, viruses, and fungi in pathogenesis of inflammatory bowel diseases and therapeutic approaches[J]. Gastroenterology, 2017, 152(2): 327-339.e4.
[48]Wang S, Liu W, Wang J, et al. Curculigoside inhibits ferroptosis in ulcerative colitis through the induction of GPX4[J]. Life Sci, 2020, 259: 118356.
[49]Mayr L, Grabherr F, Schwrzler J, et al. Dietary lipids fuel GPX4restricted enteritis resembling Crohn′s disease[J]. Nat Commun, 2020, 11(1): 1775.
[50]Chen Y, Zhang P, Chen W, et al. Ferroptosis mediated DSSinduced ulcerative colitis associated with Nrf2/HO1 signaling pathway[J]. Immunol Lett, 2020, 225: 9-15.
[51]Rahman MS, Alam MB, Kim YK, et al. Activation of Nrf2/HO1 bypeptide YD1 attenuates inflammatory symptoms through suppression of TLR4/MYyD88/NFκB signaling cascade[J]. Int J Mol Sci, 2021, 22(10): 5161.
[52]Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2021, 71(3): 209-249.
[53]Zhao L, Peng Y, He S, et al. Apatinib induced ferroptosis by lipid peroxidation in gastric cancer[J]. Gastric Cancer, 2021, 24(3): 642-654.
[54]Hao S, Yu J, He W, et al. Cysteine dioxygenase 1 mediates erastininduced ferroptosis in human gastric cancer cells[J]. Neoplasia, 2017, 19(12): 1022-1032.
[55]Wang C, Shi M, Ji J, et al. StearoylCoA desaturase 1(SCD1) facilitates the growth and antiferroptosis of gastric cancer cells and predicts poor prognosis of gastric cancer[J]. Aging (Albany NY), 2020, 12(15): 15374-15391.
[56]Hu X, Miao J, Zhang M, et al. MiRNA103a3p promotes human gastric cancer cell proliferation by targeting and suppressing ATF7 in vitro[J]. Mol Cells, 2018, 41(5): 390-400.
[57]Niu Y, Zhang J, Tong Y, et al. Physcion 8Oβglucopyranoside induced ferroptosis via regulating miR103a3p/GLS2 axis in gastric cancer[J]. Life Sci, 2019, 237: 116893.
[58]Mao SH, Zhu CH, Nie Y, et al. Levobupivacaine induces ferroptosis by miR4893p/SLC7A11 signaling in gastric cancer[J]. Front Pharmacol, 2021, 12: 681338.
[59]Sieminska I, Baran J. Myeloidderived suppressor cells in colorectal cancer[J]. Front Immunol, 2020, 11: 1526.
[60]Guo J, Xu B, Han Q, et al. Ferroptosis: a novel antitumor action for cisplatin[J]. Cancer Res Treat, 2018, 50(2): 445-460.
[61]Chen P, Li X, Zhang R, et al. Combinative treatment of βelemene and cetuximab is sensitive to KRAS mutant colorectal cancer cells by inducing ferroptosis and inhibiting epithelialmesenchymal transformation[J]. Theranostics, 2020, 10(11): 5107-5119.
[62]Sui X, Zhang R, Liu S, et al. RSL3 drives ferroptosis through GPX4 inactivation and ROS production in colorectal cancer[J]. Front Pharmacol, 2018, 9: 1371.
[63]Zhang L, Liu W, Liu F, et al. IMCA induces ferroptosis mediated by SLC7A11 through the AMPK/mTOR pathway in colorectal cancer[J]. Oxid Med Cell Longev, 2020, 2020: 1675613.
[64]Xu X, Zhang X, Wei C, et al. Targeting SLC7A11 specifically suppresses the progression of colorectal cancer stem cells via inducing ferroptosis[J]. Eur J Pharm Sci, 2020, 152: 105450.
[65]Xie Y, Zhu S, Song X, et al. The tumor suppressor p53 limits ferroptosis by blocking DPP4 activity[J]. Cell Rep, 2017, 20(7): 1692-1704.
[66]Zhang W, Gai C, Ding D, et al. Targeted p53 on smallmoleculesinduced ferroptosis in cancers[J]. Front Oncol, 2018, 8: 507.
[67]Xu C, Liu Z, Xiao J. Ferroptosis: a doubleedged sword in gastrointestinal disease[J]. Int J Mol Sci, 2021, 22(22): 12403.
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