Objective: To explore pregnancy management through risk factors analysis of adverse pregnancy outcomes. Methods: A cohort study was conducted on 872 patients excluded prepregnancy complications from August 2016 to May 2017. The following data on pregnancy and adverse pregnancy outcomes were collected, i.e. pre-pregnancy related information, pregnancy examination data, gestational week, newborn birth weight and common complications during pregnancy. The risk factors of premature birth, postpartum hemorrhage, macrosomia, low birth weight and cesarean section were analyzed by multivariate regression analysis, and the management plan was proposed according to the risk factors. Results: The risk factors of gestational hypertension were advanced age, high BMI before pregnancy, excessive weight gain and increased triglyceride level in late stage. Risk factors for gestational diabetes were advanced age, high pre-pregnancy BMI and insufficient weight gain. The main risk factors of premature birth were gestational hypertension and premature rupture of membranes. The main risk factors of postpartum hemorrhage are high pre-pregnancy weight and large fetal weight. The main risks of giving birth to giant baby at full term were excessive weight gain during pregnancy, high BMI before pregnancy and prolonged gestational period.Conclusion: The management of peri-pregnancy was suggested as that pregnancy should be conducted at an appropriate age, pre-pregnancy weight should be controlled, microelements should be added appropriately, weight growth rate should be controlled in an appropriate range during pregnancy, and reproductive tract infection should be actively screened and controlled.