Duration of proneposition ventilation influence the therapeutic effect on patients with early acute respiratory distress syndrome
caused by pulmonary diseases
YAN Jun， JI Mu-sen， JIN Zhao-chen
(Intensive Care Unit, Affiliated People′s Hospital of Jiangsu University, Zhenjiang Jiangsu 212002， China)
Abstract：Objective: To determine the efficacy of mechanical ventilation on prone position (PPV) on oxygenation and respiratory mechanics in patients with early acute respiratory distress syndrome (ARDS) resulting from pulmonary cause (ARDSp). Methods: Twenty-six ARDSp patients were placed in prone position for 6 h. The effect of different time (pre-PPV, PPV 0.5, 2, 4,6 h) on oxygenation and respiratory mechanics were observed. Results: Compared with pre-PPV, in ARDSp patients, partial pressure of oxygen in artery(PaO2)/ inhaled oxygen concentration (FiO2) was increased after 2 h PPV (224.86±30.84 vs 192.45±46.81, P=0.03). And 4 h after PPV, the PaO2/FiO2 still further raised compared with PPV 2 h (286.38±36.67 vs 224.86±30.84, P=0.00). No significant difference in the PaO2/FiO2 was found between PPV 4 h and PPV 6 h (286.38±36.67 vs 287.46±38.84, P=0.98). There was no significant difference in the respiratory system compliance between before and after the prone position ventilation(F=1.00, P=0.40). Conclusions: The PaO2/FiO2 was improved when patients with early ARDSp were ventilated on prone position, especially for 4 h PPV. ［Key words］ acute respiratory distress syndrome; prone position; oxygenation; respiratory mechanics
颜骏, 吉木森, 金兆辰. 俯卧位通气持续时间对早期肺内源性急性呼吸窘迫综合征疗效的影响[J]. 江苏大学学报:医学版, 2013, 23(6): 520-.
YAN Jun, Ji-Mu-Sen, Jin-Zhao-Chen. Duration of proneposition ventilation influence the therapeutic effect on patients with early acute respiratory distress syndrome
caused by pulmonary diseases. Journal of Jiangsu University(Medicine Edition), 2013, 23(6): 520-.
2013, Vol. 23 
