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The correlation between heart rate variability and outcome of radiofrequency catheter ablation guided by magnetic navigation system for patients with atrial fibrillation |
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Abstract Objective To explore the relationship between heart rate variability(HRV) and outcome of radiofrequency catheter ablation(RCA) guided by magnetic navigation system for patients with atrial fibrillation(AF). Methods Fifty-eight AF patients who had undergone RCA guided by magnetic navigation system were enrolled consecutively. ECG and Holter recordings were performed, and HRV was analyzed. The recurrence of AF was observed. AF recurrence was defined as recurrence of atrial tachycardia, atrial flutter or AF lasting longer than 30 seconds three months after the procedure. Results Fifty patients were enrolled finally, and were followed up for an average of (15.56±4.60) months. AF recurrence was found in 20 patients and the mean recurrence time was (6.05±4.42) months after the procedure. In the AF recurrence group, the root mean square of successive R-R interval difference, proportion of R-R intervals differing from their neighbors by >50 ms, and highfrequency component three months after the procedure were significantly higher than those in the nonrecurrence group(P=0.036, 0.045 and 0.015, respectively) while low/highfrequency ratio(LF/HF) was significantly lower(P=0.015). COX survival analysis revealed that LF/HF was an independent risk factor of AF recurrence(P=0.010). Conclusion LF/HF three months after RCA guided by magnetic navigation system for AF patients may be an independent predictor of AF recurrence.
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