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Abstract Obstructive sleep apnea(OSA), a common disease, is regarded as a risk factor of various cardiovascular diseases and paid more attention recently. OSA can impact on atria directly or indirectly by altering intrathoracic negative pressure via airway obstruction, or causing secondary changes of nervous system and humoral inflammatory factors after aspneainduced hypoxia. It is closely related to the incidence of atrial arrhythmia such as atrial premature beats and atrial fibrillation. This paper reviews the relationship between OSA and atrial arrhythmia from the three aspects of clinical research, pathophysiologic mechanism and treatment.
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