|
|
Cardiac function of young and middle-aged patients with dilated cardiomyopathy complicating heart failure |
|
|
Abstract Objective To explore the relationship between cardiac function and dilated cardiomyopathy with or without heart failure among young and middleaged patients and discuss its clinical significance. MethodsExaminations of echocardiogram and ECG were carried out on 123 patients with dilated cardiomyopathy in our hospital, among whom were 65 cases complicating heart failure(heartfailure group) and 58 cases not accompanied with the disease(nonheartfailure group). Between the 2 groups, the sizes of heart, cardiac function and the occurrence of arrhythmia were compared. ResultsCompared with nonheartfailure group, the differences in left ventricular end systolic diameter(LVESd), left ventricular end diastolic diameter(LVEDd), left atrial diameter(LAD), left ventricular ejection fraction(LVEF) and left ventricular fractional shortening(LVFS) of heartfailure group were statistically significant(P<0.01). ② The incidences of changes of QRS duration, low voltage in limb leads, abnormal Q waves and STT segment in heartfailure group were all slightly higher than those of nonheartfailure group, without statistically significant differences(P>0.05). Compared with nonheartfailure group, there were statistically significant differences(P<0.01) in the incidences of atrial arrhythmia, ventricular arrhythmia and conduction block in heartfailure group. ③ On admission, cardiac function of patients in heartfailure group was classified into level Ⅲ and Ⅳ, accounting for 58.4% and 21.5%, respectively. After treatment in hospital, cardiac function of the 2 groups both improved significantly compared with that on admission(P<0.05). ConclusionDilated cardiomyopathy is followed by obvious increase of left ventricular end diastolic diameter and significant decrease of left ventricular ejection fraction(LVEF) if accompanied with heart failure and arrhythmia while the phenomena are more or less associated with cardiac function. By getting rid of inducing factors of heart failure, early diagnosis and treatment can improve cardiac function, prognosis and life quality of patients.
|
|
|
|
|
[1] 王吉耀.内科学[M].北京:人民卫生出版社,2005:318-322.[2] 刘延玲,熊鉴然.临床超声心动图学[M].2版.北京:科学出版社,2007:868-873.[3] Komajda M,Jais JP, Reeves F,et al.Factors predicting mortality in idiopathic dilated cardiomyopathy[J].Eur Heart J,1990,11(9):824-831.[4] Maron BJ,Towbin JA,Thiene G,et al.Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes ResearchandFunctional Genomicsand Translational BiologyInterdisciplinary Working Groups;and Council on Epidemiology and Prevention[J].Circulation,2006,113(14):1807-1816.[5] Di Lenarda A,Pinamonti B,Mestronl L,et al.The natural history of dilated cardiomyopathy:a review of the Heart Muscle Disease Registry of Trieste[J].Ital Heart J Suppl,2004,5(4):253-266.[6] Stevenson WG.Middle kauff HR, Stevenson LW,et al.Significance of aborted cardiacl arrestand sustained cardiac tachy cardiain patients referred for treatment therapy of advanced heart failured [J] Am Heart J,1992,124(1):123-130.[7] 程宽,王齐兵,李高平,等.扩张型心肌病280例临床分析[J].临床心血管病杂志,2006,22(7):393-396. |
|
|
|