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| Research progress of relationship between epicardial adipose tissue and atrial fibrillation |
| ABUDURUSULI Subinuer, YASEN Alimire, YAO Juan |
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Abstract Epicardial adipose tissue (EAT) as an active endocrine tissue located on the surface of the heart, not only provides energy for the heart, but also participates in inflammatory responses and metabolic regulation. Increased amount of epicardial adipose is significantly associated with the increased incidence of atrial fibrillation (AF), potentially promoting the occurrence and persistence of AF through mechanisms such as enhancing local cardiac inflammation, increasing oxidative stress, or directly affecting the electrophysiological properties of cardiomyocytes. This paper reviews the current research status on the relationship between EAT and AF, explores their association mechanism, and proposes future research directions regarding the role of EAT in AF pathogenesis.
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