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Research advances in pericardial diseases associated with immune checkpoint inhibitors |
ZHANG Zhou, LUO Dan, TAN Mengqin, WANG Fujun |
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Abstract Immune checkpoint inhibitors (ICIs) have been widely applied in the clinical treatment of various malignant tumors by blocking the tumor immune escape. However, it is followed by increasing immunerelated adverse events caused by ICIs. As common ICIsrelated cardiovascular adverse reactions, pericardial diseases lead to a relatively high mortality at the acute phase. This article introduces the research progress in recent years on the epidemiology, pathogenesis, clinical characteristics, and treatment principles of ICIsrelated pericardial diseases, in order to deepen the clinicians understandings of this disease.
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