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| Advances in diagnosis and treatment of myocarditis caused by immune checkpoint inhibitors |
| TAN Mengqin, LUO Dan, ZHANG Zhou, WANG Fujun |
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Abstract With the wide application of immune checkpoint inhibitors (ICIs) in the field of tumor treatment, a series of immunerelated adverse reactions of cardiovascular system caused by ICIs have aroused clinicians attention. ICIsassociated myocarditis has become a focus due to its relatively low incidence but high lethality. At present, we have not known enough about the molecular mechanism and pathophysiological process of ICIsinduced myocarditis. This paper explores the pathological mechanisms of ICIsassociated myocarditis, its risk factors, clinical features, means of diagnosis and monitoring, and formulation of reasonable treatment strategies through literature review, so as to enhance clinicians alertness and ability to deal with such adverse events, and improve the prognosis of tumor patients.
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