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Abstract Objective To analyze electrocardiographic characteristics of patients with diffuse large B-cell lymphoma (DLBCL) Methods Electronic medical records of 90 patients who were pathologically diagnosed as DLBCL were retrospectively reviewed in Tianjin Medical University Cancer Institute and Hospital between December 2014 and September 2015. Clinical characteristics, incidence of abnormal electrocardiogram (ECG) and manually measured baseline hypertension electrocardiographic parameters were collected into the study. Results The mean age of the cohort was 58 years old, among which 53 cases(58.9%) were males. In these patients, 25 cases (27.8%) had a history of hypertension and 13 cases(14.4%) had a history of diabetes mellitus. Abnormal baseline ECG were discovered in 54 cases(60.0%), among which 32 cases(35.6%) showed ST-T change. The statistical results of baseline electrocardiographic are as follows: HR (83±17)beat/min, PWD (104.6±11.0)ms, PWA (0.13±0.04)mV, PtfV1 (-0.010±0.011)mm·s, Pd (37.0±10.1)ms, PRI (149±23)ms, QRSD (89.3±16.4)ms, QRS axis 46.0°±35.1°, QTc (417.6±61.5)ms , QTd (43±16)ms, TpTe (86±21)ms、iCEB 4.0±0.8. Conclusion The newly diagnosed DLBCL patients have a high morbidity of cardiovascular diseases, and more than 50% patients are combined with abnormal baseline ECG, with relatively normal electrocardiographic parameters, which should be highly concerned in clinical practice.
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