|
|
|
| Preparation and adsorption separation properties of diethylstilbestrol magnetic molecularly imprinted materials |
| YUAN Xinhua, LIU Shuai, MENG Fuliang, CHEN Zeyu, QIN Yuan, XU Chunyu, FEI Hongwei |
| 1. School of Materials Science and Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China; 2. Hangmo New Materials Group Co., Ltd., Huzhou, Zhejiang 313310, China; 3. Changzhou Haoda Technology Co., Ltd., Changzhou, Jiangsu 213133, China |
|
|
|
| Guide |
|
|
Abstract Nano-Fe3O4 was prepared by solvothermal method, and the prepared Fe3O4 nanoparticles were dispersed in tetraethyl orthosilicate（TEOS）hydrolysate to deposite a layer of silica on the surface. Methacryloxypropyltrimethoxysilane (MPS) was used for SiO2-Fe3O4 surface modification to obtain MPS-SiO2-Fe3O4. Methacrylic acid (MAA) and diethylstilbestrol (DES) were added into acetonitrile solvent with molar ratio of 4 ∶1 for 12 h self-assembly, and MPS-SiO2-Fe3O4, ethylene glycol dimethacrylate (EGDMA) and azobisisobutyronitrile (AIBN) were added for ultrasonically dispersing for 30 min with latter mechanically stirring at 65 ℃ for 24 h to obtain DES magnetic molecularly imprinted polymer (MMIP). The characterization was conducted by transmission electron microscopy, vibrating sample magnetometer and adsorption experiments. The results show that the saturation magnetic intensity of MMIP is 268 kA/m without hysteresis and with zero coercivity and super paramagnetic properties, and MMIP can be rapidly separated from the solution in 17 s under the action of magnet. At room temperature, the maximum static adsorption capacity of MMIP to DES is 7.1 mg/g, and MMIP can reach more than 90% of the maximum adsorption capacity in 60 min during dynamic adsorption. The imprinting factor of MMIP to DES is 3.70, which shows great ability to identify DES. MMIP can be reused more than six times with good renewable performance.
|
|
Received: 25 May 2022
|
|
|
| Fund: 国家自然科学基金资助项目（51808263，51603093） |
|
|
|
| ［1］ |
ROBOTTI S. The heritable legacy of diethylstilbestrol: a bellwether for endocrine disruption in humans[J]. Bio-logy of Reproduction, 2021, 105(3): 687-689.
|
| ［2］ |
TITUS L. Evidence of intergenerational transmission of diethylstilbestrol (DES) health effects: hindsight and insight[J]. Biology of Reproduction, 2021, 105(3): 681-686.
|
| ［3］ |
贺敏强，宋承成，陈永强，等. 芹菜素分子印迹聚合物的分子识别性能及机理[J]. 江苏大学学报(自然科学版)，2010, 31(5):596-600.
|
|
HE M Q, SONG C C, CHEN Y Q, et al. Recognition property and mechanism of molecularly imprinted polymers of Apigenin[J]. Journal of Jiangsu University（Natural Science Edition）,2010, 31(5):596-600.（in Chinese）
|
| ［4］ |
RUI C F, HE J, LI Y Y,et al. Selective extraction and enrichment of aflatoxins from food samples by mesoporous silica FDU-12 supported aflatoxins imprinted po-lymers based on surface molecularly imprinting technique[J]. Talanta, 2019, 201: 342-349.
|
| ［5］ |
YANG Y, MENG X G, XIAO Z G, et al. Synthesis of a surface molecular imprinting polymer based on silica and its application in the identification of nitrocellulose[J]. RSC Advances, 2018, 8(18): 9802-9811.
|
| ［6］ |
LI H, LI Y Z, LI Z P, et al. Preparation and adsorption behavior of berberine hydrochloride imprinted polymers by using silica gel as sacrificed support material[J]. Applied Surface Science, 2012, 258(10):4314-4321.
|
| ［7］ |
BULATOVA E V, PETROVA Y Y. Use of micro- and nanodimensional inorganic materials in surface molecular imprinting[J]. Journal of Analytical Chemistry, 2018, 73(8): 750-764.
|
| ［8］ |
袁新华，刘敦舜，刘怡，等. 苦参碱分子印迹氢键型超高交联吸附树脂的制备及吸附性能[J].江苏大学学报(自然科学版)，2019, 40(5): 585-590.
|
|
YUAN X H, LIU D S, LIU Y, et al. Preparation and adsorption properties of hydrogen-bonded molecular imprinting hypercrosslinked polymeric adsorbent for Matrine[J]. Journal of Jiangsu University（Natural Science Edition）,2019, 40(5): 585-590.（in Chinese）
|
| ［9］ |
LIU H C, ZHOU Y Q, QI Y X, et al. Preparation of thiamphenicol magnetic surface molecularly imprinted polymers for its selective recognition of thiamphenicol in milk samples[J]. Journal of Liquid Chromatography & Related Technologies, 2018, 41(13/14): 868-879.
|
| ［10］ |
CAI T P, MA M H, LIU H H,et al. Preparation of monodisperse magnetic surface molecularly imprinted polymers for selective recognition of lincomycin hydrochloride in milk[J]. Journal of Liquid Chromatography & Related Technologies, 2019, 42(13/14): 459-467.
|
|
|
|
