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| Role of transbronchial needle aspiration in mediastinal restaging of ⅢA-N2 non-small cell lung cancer after neoadjuvant chemotherapy |
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ZHOU Yao1, ZHUANG Zhi-fang1, JIANG Min-yan2, XUE Zhi-xin3, QIU Tie-feng1, ZHU Xiao-bo2, LING Xia-jun1, MIAO Xiao-hui1, JIANG Yi-ya1, ZHONG Ya-hua1, YIN Xiu-li1, ZHOU Yan-juan1 |
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Abstract Objective: To evaluate the clinical value and safety of transbronchial needle aspiration(TBNA) in mediastinal restaging of non-small cell lung cancer(NSCLC) after neoadjuvant chemotherapy. Methods: In 15 NSCLC patients with suspected N2 lymph node metastasis by chest CT scan, TBNA was performed for two times, before and after chemotherapy. The cytological results were compared with post-operative pathology. Results: Overall diagnostic sensitivity, specificity, accuracy, positive predictive value and negative predictive value of TBNA in mediastinal restaging after neoadjuvant chemotherapy were 80.6％, 100％, 87.2％, 100％ and 72.7％. The overall coincidence rate of pathologic typing was 80％. The overall accuracy of c-N by TBNA was 86.7 ％(13／15). Serious complications were not observed in all patients. Conclusion: TBNA is an accurate and safe method for mediastinal restaging of NSCLC, which has certain clinical application value.
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Received: 22 November 2012
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2013, Vol. 23 
