心脏超声评估肺动脉高压患者肺血管压力及右心功能的临床价值

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Abstract Objective: To evaluate the clinical value of cardiac ultrasonography in evaluating pulmonary vascular pressure and right heart function in patients with pulmonary arterial hypertension (PAH). Methods: A retrospective analysis was performed with the clinical data of 97 PAH patients suspected of right heart dysfunction(study group). Another 32 healthy people who underwent physical examination during the same period were selected as the control group. According to pulmonary artery systolic pressure (PASP) of PAH patients, they were divided into mild group (n=45), moderate group (n=32) and severe group (n=20). All study subjects underwent cardiac ultrasonography. The pulmonary artery diameter indexes ［pulmonary arterydiameter (DPA), right pulmonary artery diameter (RPAD)］, pulmonary artery blood pressure indexes ［PASP, pulmonary artery diastolic pressure (PADP), mean pulmonary artery pressure (PAPM)］ and right heart function indexes \[right ventricular ejection fraction (RVEF), right ventricular fractional area change rate (RVFAC), tricuspid annular plane systolic excursion (TAPSE), tricuspid annulus sidewall systolic velocity (s), ratio of tricuspid valve diastolic peak E and peak A (E/A value), right ventricular myocardial performance index (RMPI)\] were compared between the study group and control group, and the correlation between right heart function indexes and PASP was analyzed. Results: The DPA, RPAD, PASP, PADP, PAPM, E/A value and RMPI of PAH patients in the study group were significantly higher than those in the control group， while the RVEF, RVFAC, TAPSE and s were significantly lower than those in the control group (P<0.05). The DPA, RPAD, PASP, PADP, PAPM, E/A value and RMPI in the mild group, moderate group and severe group were gradually increased， while the RVEF, RVFAC, TAPSE and s were gradually decreased (P<0.05). RVEF, RVFAC, TAPSE and s were significantly negatively correlated with PASP (P<0.001), and E/A value and RMPI were significantly positively correlated with PASP (P<0.001). Conclusion: Cardiac ultrasonography could accurately and objectively assess the pulmonary vascular pressure and right ventricular function in patients with PAH, and provide a reliable reference for clinical diagnosis and treatment.

Received: 28 September 2020

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	ZHANG Jin1
	FENG Jian2

Cite this article:

ZHANG Jin1,FENG Jian2.

Clinical value of cardiac ultrasonography in evaluating pulmonary vascular pressure and right heart function in patients with pulmonary arterial hypertension

[J]. Journal of Jiangsu University(Medicine Edition), 2021, 31(01): 69-72.

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http://zzs.ujs.edu.cn/xbyxb/EN/ OR http://zzs.ujs.edu.cn/xbyxb/EN/Y2021/V31/I01/69

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