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Abstract Objective: To explore the relationship between magnetic resonance diffusion-weighted imaging (DWI) and Ki67 expression in invasive ductal carcinoma of the breast. Methods: A total of 42 patients with invasive ductal breast cancer were enrolled in the study from January in 2017 to December in 2018 and all patients underwent DWI scanning in the Affiliated Hospital of Jiangsu University. Ki-67 expression in tumor tissues was measured by immunohistochemical staining. The relationship between the level of Ki-67 expression and diffusion-weighted magnetic resonance imaging parameters was analyzed. Results: There were significant differences between groups in the Ki-67 expressions in breast cancer tissues, maximum crosssectional area, volume and apparent diffusion coefficient (ADC) values (F=9.332, P<0.01; F=20.509, P<0.01; F=5.634, P<0.01). Further correlation results showed that Ki67 had no correlation with the maximum cross-sectional area and volume of the tumor (r=0.335, P>0.05; r=0.817, P>0.05), while showed a significant negative correlation with the ADC value of the tumor (r=-0.589, P <0.01). Conclusion: Cell proliferation in breast cancer tissues could be associated with ADC value of diffusion sequence.
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Received: 03 June 2019
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2019, Vol. 29 
