腹腔镜与开腹经腹会阴直肠切除术治疗低位直肠癌的疗效对比：基于倾向性匹配分析

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Abstract Objective: To evaluate the advantages of laparoscopic and open abdominoperineal resection(APR) by comparing clinicopathological results of the two methods. Methods: We collected clinical data from consecutive patients who underwent APR for rectal cancer from January in 2012 to January in 2016, compared the surgical outcomes and longtime survival of a laparoscopic surgery group (LG) with those of an open surgery group (OG). Results: A total of 158 patients were analyzed, with 84 in LG and 74 in OG. A total of 139 patients were kept. Then each group had 49 cases by using propensity matching analysis (1 ∶1). The perioperative clinical and pathological factors between two groups had no significant difference. Compared with OG, LG had less intraoperative bleeding and decline of hemoglobin, albumin and globin affected by surgery, lower rate of postoperative infection of abdominal and surgical site, lighter severity degree of postoperative complications, shorter resumed oral intake time and postoperative hospitalization lengths and higher hospital charges (all P<0.05). However, there was no significant difference in prognosis between two groups (P=0.754, 95%CI: 0.467-2.864). Conclusion: The laparoscopic surgery has better shortterm and similar longterm outcomes in treating patients with rectal cancer.

Received: 09 April 2019

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http://zzs.ujs.edu.cn/xbyxb/EN/ OR http://zzs.ujs.edu.cn/xbyxb/EN/Y2019/V29/I04/351

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