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| Risk factors of pulmonary embolism in patients with AECOPD and
predictive value of Caprini thrombosis risk assessment scale |
| CHEN Wei1, FAN Jing2, AI Jiao2, LIAO Jun-zhe3 |
| （1. ICU, Third People′s Hospital of Chengdu, Chengdu Sichuan 610031; Department of Emergency，Chengdu Fifth People′s Hospital,Chengdu Sichuan 611130; Department of Respiratory Medicine, Chengdu Fifth People′s Hospital,Chengdu Sichuan 611130, China)
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Abstract Objective: To analyze the risk factors of pulmonary embolism in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD), and to explore the predictive value of Caprini thrombosis risk assessment scale on AECOPD pulmonary embolism.Methods: A total of 218 patients with AECOPD and pulmonary embolism were selected as observation group, and a total of 126 patients with AECOPD but without pulmonary embolism at the same time period were selected as control group. Logistic regression analysis was used to investigate the risk factors for pulmonary embolism in hospitalized patients with AECOPD. The Caprini score was compared between the two groups, and the relationship between Caprini score and risk of AECOPD pulmonary embolism was explored.Results: The incidences of diabetes, malignant tumor, lower extremity trauma, surgery within 6 weeks, cerebrovascular accident, and prolonged bed rest were significantly higher in the observation group than those in the control group(P0.05). History of diabetes mellitus, history of malignant tumor, history of surgery within 6 weeks, history of lower extremity trauma, history of cerebrovascular accident and longterm bedridden were independent risk factors for pulmonary embolism(P<0.05). The Caprini score in observation group was significantly higher than that in control group(P<0.05). In observation group, 117 patients(53.67%) were at extremely high risk and 53 patients(24.31%) were at high risk, and the proportion of high risk and above accounted for 77.98%. In control group, 66 patients(52.37%) were at moderately high risk and 36 cases(28.57%) were at low risk. There was a statistically significant difference in the composition ratio of risk grades between the two groups(P<0.05). Caprini risk is classified as a highrisk and highrisk AECOPD patient at high risk for pulmonary embolism. With the increase of Caprini risk grades, the risk of pulmonary embolism was significantly increased(P<0.05). Conclusion: The risk factors for pulmonary embolism in patients with AECOPD are history of diabetes mellitus, history of malignant tumor, history of surgery within 6 weeks, history of lower extremity trauma, history of cerebrovascular accident and longterm bedridden. The Caprini thrombosis risk assessment scale can be used for AECOPD pulmonary embolism and prognosis assessment.
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Received: 11 February 2019
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2019, Vol. 29 
