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阿霉素肾病动物模型的研究进展 |
郭继光1,白杨2,周广滨3 |
(1.河北大学医学部微生物学教研室, 河北 保定 071002; 2.河北大学公共外语教研部, 河北 保定 071002; 3.高碑店市医院神经外科, 河北 高碑店 074000) |
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Systemic factors are involved in the pathogenesis of proteinuria-induced glomerulosclerosis in adriamycin nephrotic rats\[J\]. J Am Soc Nephrol, 1999, 10(11): 2359-2366.\[23\]Ochodnicky P, Henning RH, Buikema H, et al. Renal endothelial function and blood flow predict the individual susceptibility to adriamycininduced renal damage\[J\]. Nephrol Dial Transplant, 2009, 24(2): 413-420.\[24\]Sakemi T, Ohtsuka N, Tomiyoshi Y, et al. Sex difference in progression of adriamycin-induced nephropathy in rats\[J\]. Am J Nephrol, 1996, 16(6): 540-547.\[25\]Wang Y, Wang YP, Tay YC, et al. Progressive adriamycin nephropathy in mice: sequence of histologic and immunohistochemical events\[J\]. Kidney Int, 2000, 58(4): 1797-1804.\[26\]Zheng Z, SchmidtOtt KM, Chua S, et al. A Mendelian locus on chromosome 16 determines susceptibility to doxorubicin nephropathy in the mouse\[J\]. Proc Natl Acad Sci USA, 2005, 102(7): 2502-2507.\[27\]Zheng Z. An ancestral haplotype defines susceptibility to doxorubicin nephropathy in the laboratory mouse\[J\]. J Am Soc Nephrol, 2006, 17(7): 1796-1800.\[28\]Kastner S, Fels LM, KoobEmunds L, et al. Effects of adriamycin on the balance of glomerular protein metabolism: studies in isolated glomeruli of the atlantic hagfish, myxine glutinosa\[J\]. Cell Physiol Biochem, 1995, 5(6): 399-407\[29\]Barbey MM, Fels LM, Soose M, et al. Adriamycin affects glomerular renal function: evidence for the involvement of oxygen radicals\[J\]. Free Radic Res Commun, 1989, 7(3/6): 195-203.\[30\]Guo J, Ananthakrishnan R, Qu W, et al. RAGE mediates podocyte injury in adriamycin-induced glomerulosclerosis\[J\]. J Am Soc Nephrol, 2008, 19(5): 961-972. |
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